New sesquiterpenoid derivatives from Solanum septemlobum with cytotoxicities Lei Zhang, Hai-Qing Lin, Gui-Sheng Li, Xi-Dian Yue & ShengJun Dai a School of Pharmaceutical Science, Yantai University, Yantai 264005, P.R. China b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical Coll...

This article examines the scope for strategies to build natural assets in the hands of low-income individuals and communities. Natural assets include sources of raw materials such as forests and fisheries, and the airsheds, lands, and water bodies that provide environmental sinks for the disposal of wastes. These resources become assets when people have rights to access their benefits. Four str...

Recent research on the chemistry of natural products from the author's group that led to the receipt of the ACS Ernest Guenther Award in the Chemistry of Natural Products is reviewed. REDOR NMR and synthetic studies established the T-taxol conformation as the bioactive tubulin-binding conformation, and these results were confirmed by the synthesis of compounds which clearly owed their activity ...

The quinolones have evolved from antibacterial agents with a limited spectrum of predominantly anti-gram-negative antimicrobial activity and a restricted number of indications to a class of widely used oral (and, in some cases, intravenous) antibiotics with extensive indications for infections caused by many bacterial pathogens in most body tissues and fluids. This evolutionary pattern has aris...

Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activities in vitro Filomena Conforti a , Federica Menichini a , Carmen Formisano b , Daniela Rigano b , Felice Senatore b , Maurizio Bruno c , Sergio Rosselli c & Sezgin Çelik d a Department of Pharmaceutical Sciences , University of Calabria , via ...

We propose a model of natural language inference which identifies valid inferences by their lexical and syntactic features, without full semantic interpretation. We extend past work in natural logic, which has focused on semantic containment and monotonicity, by incorporating both semantic exclusion and implicativity. Our model decomposes an inference problem into a sequence of atomic edits lin...

Rodriguez Villegas expressed the Mahler measure of a polynomial in terms of an infinite series. Lück’s combinatorial L-torsion leads to similar series expressions for the Gromov norm of a knot complement. In this note we show that those formulae yield interesting power series expansions for the logarithm function. This generalizes an infinite series of Lehmer for the natural logarithm of 4. 1 T...

A wound is a disruption of the normal anatomical structure and function of a tissue. Wounds cure in an orderly and timely repair process which is characterized by three dynamic and interactive phases: inflammation, proliferation and the remodeling. The present review was designed to elaborate the cellular and molecular targets for plant secondary metabolites that target the various aspects of w...

An impressive abundance of high quality scientific content about Earth’s biodiversity and natural history available in Natural History Museums (NHMs) around Europe remains largely unexploited due to a number of barriers, such as: the lack of interconnection and interoperability between the management systems used by museums, the lack of centralized access through a European point of reference l...

Exposed disagreement is extremely rare in natural dialogue. Although informal argumentation features frequently in natural dialogue, the ways in which individuals make and evidence claims and position their opinions in relation to those of others is often achieved through more subtle and oblique methods. This makes natural dialogue distinct from more formal or institutionalised contexts. With i...