Bovine viral diarrhea viruses are economically important pathogens of cattle. Most infections in susceptible animals are acquired from animals persistently infected with the virus. Surveillance programs rely on skin biopsies of persistently infected (PI) cattle to detect the infection. The purpose of this study was to compare antigen capture enzyme-linked immunosorbent assay (ACE) testing resul...

A reliable antemortem diagnostic method is needed for determining infection with canine distemper virus (CDV). The utility of immunohistochemical detection of CDV antigen was examined was examined for samples of nasal and footpad epithelium and haired skin in dogs with and without detectable CDV antigen in the lung and/or brain. Tissues from 57 dogs at risk of CDV infection were tested. Viral a...

Local allergic rhinitis is a newly described type of rhinitis involving nasal production of specific immunoglobulin (slg) E antibodies in the absence of atopy. It can affect patients previously diagnosed with non-allergic rhinitis. Evidence for this entity is supported by clinical symptoms, local production of slgE, a type 2 helperT cell inflammatory pattern in nasal secretions during natural e...

BACKGROUND The site, size, and depth of tissue loss, irradiation, or composite injury to adjacent cheek and lip may make local tissues inadequate or unavailable for the repair of major nasal defects. METHODS In 13 patients, a single, folded, horizontal radial forearm flap was used to line the vault and columella, with an incontinuity fasciocutaneous extension to resurface the nasal floor, wit...

Photoaging of the skin depends primarily on the degree of ultraviolet radiation (UVR) and on an amount of melanin in the skin (skin phototype). In addition to direct or indirect DNA damage, UVR activates cell surface receptors of keratinocytes and fibroblasts in the skin, which leads to a breakdown of collagen in the extracellular matrix and a shutdown of new collagen synthesis. It is hypothesi...

BACKGROUND In critically ill patients, clinicians can have difficulty obtaining accurate oximetry measurements. OBJECTIVE To compare the accuracy of nasal alar and forehead sensor measurements and incidence of pressure injury. METHODS 43 patients had forehead and nasal alar sensors applied. Arterial samples were obtained at 0, 24, and 120 hours. Oxygen saturations measured by co-oximetry we...

rhinosporidiosis is a granulomatous disorder caused by rhinosporidium seeberi, an aquatic parasite. it spreads through contaminated water and soil. it frequently involves the nasal cavity and nasopharynx. disseminated or systemic lesions are rare. a 56 year old man presented with multiple tumor like lesions all over the body in our cancer institute in april 2012. fine needle aspiration cytology...

Figure 1. Yellow-black discoloration of upper palate. Figure 2. Paranasal sinus CT scan revealed a defect of the nasal septum and skin and subcutaneous edema.

OBJECTIVES/HYPOTHESIS Chronic Rhinosinusitis (CRS) is accompanied by evidence of a vigorous adaptive immune response, and emerging studies demonstrate that some nasal polyps manifest a polyclonal autoantibody response. We previously found that antibodies against BP180, a component of the hemidesmosome complex and the dominant epitope in autoimmune bullous pemphigoid, were found at elevated leve...

A 29-year-old male patient with extranodal NK/T-cell lymphoma, a nasal type lymphoma with involvement of skin as the first symptom, was reported. The patient presented with swelling in the left side of the nose and suffered intermittent fever for 1 month. The fester in the oral mucosa and skin under the left nostril and redness, and the swelling on the orbit of the left eye lasted for 1 week. P...