نتایج جستجو برای: namd

تعداد نتایج: 319  

Journal: :International Journal of Cloud Computing and Services Science (IJ-CLOSER) 2012

Journal: :Híradástechnika 2022

The increasing gap between computing speed and storage latency leads to possible I/O bottlenecks on massively parallel computers. To mitigate this issue, hierarchical provides multi-tiered configurations where each tier has its own physical characteristics associated performance. Selecting the most appropriate file placement policy is difficult there our knowledge no tool that systematically st...

Journal: :Health technology assessment 2015
Usha Chakravarthy Simon P Harding Chris A Rogers Susan Downes Andrew J Lotery Helen A Dakin Lucy Culliford Lauren J Scott Rachel L Nash Jodi Taylor Alyson Muldrew Jayashree Sahni Sarah Wordsworth James Raftery Tunde Peto Barnaby C Reeves

BACKGROUND Bevacizumab (Avastin®, Roche), which is used in cancer therapy, is the 'parent' molecule from which ranibizumab (Lucentis®, Novartis) was derived for the treatment of neovascular age-related macular degeneration (nAMD). There were reports in the literature on the effectiveness of bevacizumab in treating nAMD, but no trials. The cost per dose of bevacizumab is about 5-10% that of rani...

2017
Kimberly Spooner Thomas Hong Wijeyanthy Wijeyakumar Andrew A Chang

PURPOSE To systematically review anatomical and functional outcomes subsequent to switching from bevacizumab/ranibizumab to aflibercept monotherapy in patients with treatment-resistant neovascular age-related macular degeneration (nAMD). DESIGN Systematic review and meta-analysis. METHODS Medline, PubMed, Embase, and Cochrane databases were searched up to July 2016 for available scientific ...

Journal: :Clinical ophthalmology 2016
Philip Hykin Usha Chakravarthy Andrew Lotery Martin McKibbin Jackie Napier Sobha Sivaprasad

PURPOSE AURA was an international, retrospective, observational study that monitored the real-life use and effectiveness of ranibizumab injections in patients with neovascular age-related macular degeneration (nAMD). This paper reports the findings from the UK. METHODS Patients who started treatment with ranibizumab between January 1, 2009, and August 31, 2009, and had documented follow-up to...

Journal: :Ophthalmic epidemiology 2016
Eric H Souied Pravin U Dugel Alberto Ferreira Ron Hashmonay Jingsong Lu Simon P Kelly

PURPOSE Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents including ranibizumab and aflibercept are used to treat patients with ocular disorders such as neovascular age-related macular degeneration (nAMD); however, the injections are associated with rare instances of severe ocular inflammation. This study compared severe ocular inflammation rates in patients treat...

Journal: :The British journal of ophthalmology 2016
Katja Hatz Christian Prünte

BACKGROUND Treat and extend (TE) treatment regimens have the potential to reduce the treatment burden placed upon patients receiving ranibizumab for neovascular age-related macular degeneration (nAMD). This study aimed to analyse changes in best corrected visual acuity (BCVA) and anatomical parameters in patients switching from a pro re nata (PRN) to a TE regimen during routine clinical practic...

Journal: :Ophthalmic research 2016
Mingxing Wu Yunan Guo Yanran Ma Zheng Zheng Qian Wang Xiyuan Zhou

BACKGROUND With the increasing number of studies indicating that two single-nucleotide polymorphisms (SNPs), rs1061170 and rs1410996, in complement factor H (CFH) might be associated with the susceptibility to age-related macular degeneration (AMD), the exact association still remains uncertain. Thus, we conducted a meta-analysis to systematically summarize and clarify the association between t...

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