Psoriasis is widely diffused in the World, with the exception of a few populations, such as the natives from Alaska and Australia, where it is unknown. Its average prevalence is about 3-4%. This is probably an underestimate, for it is mostly based on self-reports. In fact, on the one hand minimal psoriasis, e.g. nail disease, could remain undiagnosed; on the other, precise classification criter...

Previous studies have suggested a benefit for patients with plaque psoriasis when omega-3 fatty acids are added to topical treatment. This study evaluated the efficacy of a nutritional complement rich in omega-3 fatty acids in patients with mild or moderate plaque psoriasis. Thirty patients were recruited, 15 of whom were given topical treatment with tacalcitol, forming the control group. The r...

Background: Psoriasis is an immune-mediated inflammatory papulo-squamous disorder presenting as chronic plaque, pustular, erythrodermic, nail, scalp, drug induced, inverse, guttate etc. Palmoplantar psoriasis causes significant functional, cosmetic and psychological disability. Apremilast a relatively newer being PDE-4 inhibitor, having negligible adverse effects with minimum blood monitoring. ...

British Journal of DermatologyVolume 184, Issue 3 p. e92-e92 Plain Language SummaryFree Access Treatment with secukinumab is highly effective in clearing nail psoriasis: long-term results from the TRANSFIGURE clinical trial First published: 05 March 2021 https://doi.org/10.1111/bjd.19769AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare ful...

Psoriasis is a chronic relapsing disorder that involves the skin, nails and joints. With regard to the role of the immune system in psoriasis, the current study compared serum IgE concentration in patients with psoriasis with control group. Current case-control study was conducted in Dermatology clinic of Razi hospital, Tehran University of medical sciences, Tehran, Iran in 2012. Fifty-eight pa...

background: psoriasis is a disease which may have a direct impact on the psychological and social aspects of the patient, particularly due to its visibility. to date, we are unaware of any study showing a relationship between psoriasis and psychological parameters such as psychological vulnerability and coping strategies . objective: the aim of this study was to evaluate the effects of psoriasi...

The present study was to formulate a transungual drug delivery formulation. We targeted to formulate and evaluate fluconazole film for the nail fungal infection using extracted natural and evaluated penetration enhancer (PE). Model drug fluconazole was formulated with the natural extracted penetration enhancer with different ratios. The solvent for PE extraction was methanol and that extracts w...

Psoriasis is a common inflammatory, hyperproliferative skin disorder that affects 1% to 2% of the world population. The clinical diagnosis of psoriasis is relatively easy, especially when the lesions consist of erythematous, silvery white scaly, sharply demarcated, indurated plaques. Psoriasis is a chronic dermatosis of genetic origin, often precipitated by an event such as an infection, an inj...