A 24-year old female patient with acute lymphoblastic leukemia was treated with the induction therapy of the GIMEMA ALL protocol based on vincristine, daunorubicin, asparaginase and prednisone. In the second month of therapy, she was found to have white bands on all her fingernails. There were two bands on each fingernail (Figure), but her toenails were not affected. It was observed that the tr...

INTRODUCTION Nail involvement is common in psoriasis and has a considerable impact on patient quality of life. Its clinical presentation depends on which part of the nail is affected: the bed or the matrix. Fifty percent of patients report associated pain. In this study, we analyzed the safety and effectiveness of tazarotene 0.1% in a hydrophilic ointment in the treatment of nail psoriasis. M...

The aim of this study was to test the hypothesis that a reinforced gamma nail for the fixation of subtrochanteric fractures would experience less stress during loading compared with a common gamma nail. The issue of whether the use of the stronger implant would result in more stress shielding in the surrounding bone was also addressed. A finite element analysis (FEA) of a synthetic bone was emp...

BACKGROUND/AIM Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. To our knowledge, no studies to date pertain to the profile of nail changes in IBD, except for onychomycosis. We aimed to study the frequency and pattern of nail changes among patients with IBD and evaluate their potential relationships with several parameters in IBD. MATERI...

We compared the outcome of patients treated for an intertrochanteric fracture of the femoral neck with a locked, long intramedullary nail with those treated with a dynamic hip screw (DHS) in a prospective randomised study. Each patient who presented with an extra-capsular hip fracture was randomised to operative stabilisation with either a long intramedullary Holland nail or a DHS. We treated 9...

©2018 by Anais Brasileiros de Dermatologia Dear Editor, Onychomatricoma (OM) is a rare benign neoplasm of nail matrix origin. The disease was first described by Baran and Kint in 1992 in a report of three cases.1 In some cases, it may present itself with important nail dystrophy, which makes its diagnosis a challenge. We report a rare case of OM in which we discussed the clinical and dermoscopi...

Median canaliform nail dystrophy is an unusual condition of the nail, most often affecting the thumb (1). It is characterized by a longitudinal split or canal in the nail with small transversal fissures, in a fir-tree configuration. The condition is diagnosed based on its clinical features (2, 3). While the underlying mechanism is unknown, it has been suggested that median canaliform nail dystr...

and knee motion for positioning. Flex the hip to almost 90°. Remove the proximal and distal locking screws in standard fashion. Lay a guidewire on the thigh and obtain a fluoroscopic image of the proximal hip. Adjust the wire to coincide with the femoral nail on the lateral view. Draw a line along the wire, extending it onto the buttock. Externally rotate the thigh and mark a line in a similar ...

BACKGROUND In the phase III double-blind Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis (ESTEEM) 1 and 2, apremilast, an oral phosphodiesterase 4 inhibitor, demonstrated efficacy in moderate to severe psoriasis. OBJECTIVE We sought to evaluate efficacy of apremilast in nail/scalp psoriasis in ESTEEM 1 and 2. METHODS A total of 1255 patients were randomized (2:1)...

UNLABELLED Fractures of the femoral shaft treated with interlocking nails will ultimately result in breakage of the nail if the bone does not unite. Further management requires removal of the broken nail which may be a difficult process for the distal segment. If we can identify the symptoms just before the nail breaks, an exchange nailing becomes much easier. We present a patient with fibromat...