In October 1936 I was consulted regarding the painful condition of the thigh of the son of a government servant in the employ of the Military Engineering Service. For over six months the boy had been complaining of increasing pain and difficulty in the right thigh on walking. The father thought that his son had always been weak on the right leg, but that recently the boy had been quite lame, an...

Byungchul Cha ([email protected]) teaches at Muhlenberg College in Allentown, Pennsylvania, after working for three years at Hendrix College. He received his B.S. from the Korea Advanced Institute of Science and Technology, and his Ph.D. from Johns Hopkins University. His area of specialization is number theory. When he is not teaching calculus, he enjoys engaging his young son in doing other ...

A 55 year old driver left after Fajr prayer to the vegetable market to buy a few things for his daughter’s wedding lunch. While trying to avoid a big pothole in the middle of the road, he was hit by a truck without headlights coming from the opposite direction. The truck driver continued driving as if nothing had happened. None of the road users cared to help the victim but he was able to conta...

BACKGROUND Previous reports of chromosomal aberrations in different forms of congenital diaphragmatic hernia have been described as comprising aneuploidies (for example, trisomy 21), microdeletions, and duplications (for example, monosomy 15q24, 22q11.2). CASE PRESENTATION We describe the first association of a de novo partial tetrasomy 4q35.2 in a father with left-sided, isolated renal agene...

Leonardo da Vinci was born on the 15th of April, 1452, during the great "rebirth" the Renaissance. He was born in the country village of Vinci, which lies high up on the Mount Albano, in the valley of the river Arno, dividing Florence from Pisa. This lovely village remains un-spoilt today. He was the son of Caterina, a peasant girl. He was illegitimate. His father, Ser Piero da Vinci, the son o...

André, and some of the art dealers of the time. They visited him frequently and brought interesting people with them such as Rodin and Matisse, who visited Cagnes-sur-Mer a couple of times (fig 17). His cook and his chauffeur were devoted to him. The cook carried him in her arms around the house or garden, and his chauffeur drove him everywhere until the last months of his life, stopping at all...

BACKGROUND The ATP7A gene encodes the ATP7A protein, which is a trans-Golgi network copper transporter expressed in the brain and other organs. Mutations in this gene cause disorders of copper metabolism, such as Menkes disease. Here we describe the novel and unusual mutation (p.T1048I) in the ATP7A gene of a child with Menkes disease. The mutation affects a conserved DKTGT1048 phosphorylation ...