Abstract Background Inflammatory bowel disease (IBD) can be a very debilitating and it is found to more extensive in children with rapid early progression. The successful transition of patients from paediatric adult-oriented services essential prevent disruption care negative effects on long-term health outcomes. In particular, the attendance at first adult visits are pivotal phase process ensu...

A one-pot synthesis of isotopically labeled R-[6-xH]N5,N10-methylene-5,6,7,8-tetrahydrofolate (CH2H4F) is presented, where x=1, 2, or 3 represents hydrogen, deuterium, or tritium, respectively. The current procedure offers high-yield, high-purity, and microscale-quantity synthesis. In this procedure, two enzymes were used simultaneously in the reaction mixture. The first was Thermoanaerobium br...

It is well known that phenolate anions react with benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans) to afford phenazine N,N-dioxide derivatives. These are obtained through an heterocycle expansion process by reaction of the corresponding 1,2,5-oxadiazole system with the phenolate carbanion generated in basic medium attacking one of the heterocyclic nitrogen (Figure 1). When substituted benz...

Narasin is an antibacterial agent that may change rumen fermentation. Two experiments were proposed to evaluate the efficiency of narasin inclusion for lambs fed a diet containing high amounts ground flint corn. Thirty rumen-cannulated wethers used nutrient digestibility, nitrogen balance, and metabolism (Exp. 1); forty-five performance 2) animals with corn diets. The experimental diets were: c...