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تعداد نتایج: 1067125 فیلتر نتایج به سال:
C O N T E N T S . PAGE INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 HISTORICAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 REPORT OF CASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
The cover image is based on the Original Article Comprehensive characterization of Alu-mediated breakpoints in germline VHL gene deletions and rearrangements patients from 71 families by W. Marston Linehan et al., https://doi.org/10.1002/humu.24194.
The cover image is based on the Original Article VIP-HL: Semi-automated ACMG/AMP variant interpretation platform for genetic hearing loss by Zhiyu Peng et al., https://doi.org/10.1002/humu.24277.
The 40–42 residue amyloid -protein (A ) plays a central role in the pathogenesis of Alzheimer’s disease (AD). Of the two main alloforms, A 40 and A 42, the longer A 42 is linked particularly strongly to AD. Despite the relatively small two amino acid length difference in primary structure, in vitro studies demonstrate that A 40 and A 42 oligomerize through distinct pathways. Recently, a discret...
OBJECTIVE To compare the predictive accuracy of β-amyloid (Aβ)1-42 and total tau in CSF, hippocampal volume (HCV), and APOE genotype for Alzheimer disease (AD)-type dementia in subjects with amnestic mild cognitive impairment (aMCI) and nonamnestic mild cognitive impairment (naMCI). METHODS We selected 399 subjects with aMCI and 226 subjects with naMCI from a multicenter memory clinic-based c...
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