A 44-year-old male patient with known Becker muscular dystrophy and concomitant non-ischemic dilated cardiomyopathy presented to our department because of worsening heart failure and presyncope. Upon admission, the patient was in New York Heart Association functional class III despite optimal pharmacological treatment; his ECG showed sinus rhythm with left bundle branch block and a wide QRS com...

CALARESU, FRANCO R., AND GORDON J. MOGENSON. Cardiovascular responses to electrical stimulation of the septum in the rat. Am. J. Physiol. 223(4): 777-782. 197 2 .-Cardiovascular responses to electrical stimulation of histologically verified sites in the septum were studied in 60 rats. In animals under a-chloralose anesthesia stimulation of the lateral septum (24 sites) elicited arterial hypoten...

BACKGROUND Although cardiac fibroma has been regarded as benign tumor, it presents various symptoms and may lead to death. Unfortunately, only a few studies have reported the epidemiology, embryology, and histopathology of the tumor, and the factors predicting poorer outcome are still obscured. METHODS In July 2011 we searched for English and Japanese cases of cardiac fibroma using the PubMed...

It has been found that after pulmonary valvotomy for pulmonary valvular stenosis with an intact interventricular septum a satisfactory fall in right ventricular pressure is not always achieved immediately. In order to explain this, Kirklin, Connolly, Ellis, Burchell, Edwards, and Wood (1953) concluded that before the development of open heart surgery there were two main reasons: (1) failure to ...

OBJECTIVES The objectives of this study were to describe and compare two techniques used to correct nasal septum deviations located in the dorsal and/or caudal septum. STUDY DESIGN The authors conducted a retrospective clinical chart review. METHODS The authors conducted a comparison of functional and technical results between surgery in the L-strut of the septum in 114 patients with septal...

The development of olfactory bulb projections that form the lateral olfactory tract (LOT) is still poorly understood. The septum and the olfactory cortex have been shown to secrete diffusible factors repelling olfactory axons in vitro and are likely to cause the axons to avoid the septum region in vivo. Slit2, a member of the Slit gene family, has been proposed to be this septal factor based on...

ALTHOUGH TWO NINETEENTH CENTURY French pathologists1 2 and an early twentieth century German pathologist3 described cardiac pathological findings compatible with what we know today as "6asymmetrical hypertrophy of the heart," it remained for Donald Teare to bring attention to this entity in 1958.4 In nine cases of sudden death, Teare described a marked hypertrophy and thickening of the interven...

Why does the heart beat? This question--known as the myogenic versus neurogenic theory--dominated cardiac research in the 19th century. In 1839, Jan Evangelista Purkinje discovered gelatinous fibers in the ventricular subendocardium that he thought were muscular. Walter Gaskell, in 1886, demonstrated specialized muscle fibers joining the atria and ventricles that caused "block" when cut and fou...

Why does the heart beat? This question—known as the myogenic versus neurogenic theory—dominated cardiac research in the 19th century. In 1839, Jan Evangelista Purkinje discovered gelatinous fibers in the ventricular subendocardium that he thought were muscular. Walter Gaskell, in 1886, demonstrated specialized muscle fibers joining the atria and ventricles that caused “block” when cut and found...

Intracerebroventricular administration of corticotropin-releasing hormone (CRH) elicits a constellation of behavioral, autonomic, and endocrinological changes typically observed in stress. One of the behavioral changes after intracerebroventricular CRH is a profound increase of startle amplitude (CRH-enhanced startle). The present study examined the role of the septum in CRH-enhanced startle. T...