objective: the main purpose of this study was to investigate the effectiveness of lazarus multimodal psychotherapy (mmt) on perceived stress in individuals with multiple sclerosis (ms). methods: through a quasi-experimental design, forty patients in qazvin city in iran were selected by convenient sampling and then divided into two groups: experimental and control groups. after group assignment,...

conclusions this study showed that mbsr training can reduce mean depression, anxiety and stress scores in patients with ms. these findings suggest that mbsr is useful for psychological problems such as depression, anxiety and stress in patients with ms. patients and methods this randomized controlled clinical trial was performed in 2013 in ahvaz ms society. forty eight patients were selected by...

background: to evaluate safety and efficacy of percutaneous release of trigger finger in multiple digits involvement in comparison with  single digit involvement.   method: a number of 100 patients (131 fingers) were treated by percutaneous release and divided into two groups: single digit (group a) and multiple digits (group b). they were followed up for one year. success rate, pain, complicat...

background: recent studies have demonstrated controversial results and somewhat increased frequency of multiple  sclerosis  (ms). we reevaluated  the  files of  ms patients  from qom province of iran in order to investigate the epidemiology of the disease. methods:   demographic   and  clinical records  of  592  ms patients  were reviewed, which included; age, sex, date  of birth, marital and o...

multiple sclerosis (ms) is a chronic auto-immune disease. most therapeutic strategies for treatment of this disease direct immune modulation and control of inflammatory processes. first-line therapeutic agents showed moderate efficacy and frequent side-effects with moderate efficacy in trials. their parental administration and limited long-term adherence restrict their efficacy compared with se...

background: neuromyelitis optica (nmo) is an uncommon neuro- inflammatory syndrome that has shown to be distinct from multiple sclerosis (ms) and associated with the autoantibody marker nmo-immunoglobulin g (igg). there are still only a few studies regarding the epidemiology of nmo in iran. in the present study, we tried to describe the epidemiology of nmo in khuzestan as one of the densely pop...

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background: the aim of this preliminary study was to assess the safety and efficacy of high-dose oral vitamin d3 supplementation during pregnancy in women with multiple sclerosis (ms) in isfahan, iran. methods: in a single center open-label randomized, controlled clinical phase i/ii pilot study, 15 pregnant women with confirmed ms with low serum 25-hydroxyvitamin d (25(oh)d) levels were randoml...

background: available evidence shows that tetracycline family has cellular and molecular mechanisms to protect neurons and oligodendrocytes by modulating matrix metalloproteinases. we tried to compare the effectiveness of intramuscular and subcutaneous interferon beta-1a (inf-β1a) in combination with oral doxycycline among patient with relapsing remitting multiple sclerosis (rrms) and secondary...

evaluation of enlarged follicles with unerupted teeth is always important because some changes may occur. one of the extremely rare conditions seen in dental follicles is multiple calcifying hyperplastic dental follicle. we report a case of multiple calcifying hyperplastic dental follicle. radiographs showed that mandibular third molars had a pericoronal radiolucent zone delineated by a well-de...