multifunctional nanomaterials showed graet advantages in drug delivery. folic acid (fa) binding protein, a glycosyl phosphatidyl inositol anchored cell surface receptor for folate, is overexpressed in several human tumors, whereas it is highly restricted in normal tissues. therefore, in this study, fa, polyethylene glycol (peg), and fe3o4 nanoparticles multifunctionalized short multiwall carbon...

hydatid disease is a common and major public health issue caused by parasite echinococcus granulosus . the highest prevalence of the parasite can be found in different parts of world like africa, australia, and south america. this infection can occurs in almost any part of the body. here we present clinical, radiological, histological features and treatment of a multi ve­sicular osseous hydatid...

this paper is a research on the ordering planning of a supply chain with one supplier, multi buyer and multi deteriorating items. items have fixed life time and expire dates. the ordering period is taken as variable and must be computed the proposed models. the problem is studied via two different approaches the first is the joint replenishment, based on the hwang and chew's model [3] and ...

this paper presents a multi-objective linear programming model for disaster blood supply chain in some periods of time after disaster. this model assist to determine the quantity and location of facilities and also how to allocate blood to facilities. in this study, a three-level model is described, while blood is collected from temporary and permanent facilities and sent to blood center. blood...

this paper presents the formulation and solution of the combinatorial multi-mode resource constrained multi-project scheduling problem. the focus of the proposed method is not on finding a single optimal solution, instead on presenting multiple feasible solutions, with cost and duration information to the project manager. the motivation for developing such an approach is due in part to practica...

hydrocarbons are ubiquitous in daily life and include plant and animal fats, alcohols, solvents, natural gas, petroleum derivates. majority of intoxication reports of hydrocarbons are due to inhalation or ingestion, but there is few reports about intravenous injection of gasoline. we report a 58 year-old man who injected gasoline intravenously for suicide. he developed soft tissue necrosis of f...

This paper considers the reliable multi-product multi-vehicle multi-type link logistics network design problem (RMLNDP) with system disruptions, which is concerned with facilities locating, transshipment links constructing, and also allocating them to the customers in order to satisfy their demand on minimum expected total cost (including locating costs, link constructing costs, and also expect...

The multi-objective optimization for a multi-product multi-period four-echelon supply chain network consisting of manufacturing plants, distribution centers (DCs) and retailers each with uncertain services and uncertain customer nodes are aimed in this paper. The two objectives are minimization of the total supply chain cost and maximization of the average number of products dispatched to custo...