Abstract Objective: The client presents with partial deletion of chromosome 18q and duplication 18p, occurring in 1 55,000 individuals less than 1,000,000 individuals, respectively. Deletions are often characterized by hypotonia, seizures, psychomotor retardation, intellectual disability. Duplications 18p disability, epilepsy, developmental delay, attention deficits. Method: is a 5-year-old mal...

Motor vehicle crashes are the leading cause of death and acquired disability in children over age 1 in the United States. In 1998 alone, 697 children under age 6 died as occupants in motor vehicles, and nearly 100,000 were injured. This Issue Brief describes findings from Partners for Child Passenger Safety, the nation's largest surveillance system of children in car crashes, and points to impr...

The aim of this study was to investigate the effect of errors during practice on motor skill learning in young individuals with cerebral palsy (CP). Minimizing errors has been validated in typically developing children and children with intellectual disabilities as a method for implicit learning, because it reduces working memory involvement during learning. The present study assessed whether a...

OBJECTIVE To define the long-term outcome in Gilles de la Tourette syndrome (GTS) using objective rating measures. BACKGROUND Previous historical studies suggest spontaneous improvement of tic symptoms after adolescence, but objective longitudinal data are limited. METHODS The authors reviewed all videotapes in their database (1978 through 1991) of children with GTS (ages 8 to 14) who were ...

OBJECTIVE Tropical Spastic Paraparesis/HTLV-I Associated Myelopathy (TSP/HAM) is a chronic myelopathy, and pain has been mentioned as a frequent sensory symptom in this condition. The authors aimed at analyzing this symptom in a TSP/HAM patients series. METHOD For this, 46 patients were analyzed considering demographic and clinical characteristics and complaint of pain as to verbal descriptio...

The objective of the study was to treat fatigue in patients with multiple sclerosis (MS) by a neurocognitive rehabilitation program aimed at improving motor planning by using motor imagery (MI). Twenty patients with clinically definite MS complaining of fatigue were treated for five weeks with exercises of neurocognitive rehabilitation twice a week. Patients were evaluated by Fatigue Severity S...

BACKGROUND/AIM Diabetic polyneuropathy is defined as the presence of clinical or subclinical symptoms and/or signs of peripheral nerve damage in patients with diabetes mellitus in the absence of the other causes of peripheral neuropathy. The aim of this study was to assess health-related quality of life (HRQoL) in patients with diabetic polyneuropathy and its correlation with clinical and neuro...

BACKGROUND Among the 21 annotated genes at Xq22.2, PLP1 is the only known gene involved in Xq22.2 microdeletion and microduplication syndromes with intellectual disability. Using an atypical microdeletion, which does not encompass PLP1, we implicate a novel gene GLRA4 involved in intellectual disability, behavioral problems and craniofacial anomalies. CASE PRESENTATION We report a female pati...

BACKGROUND AND PURPOSE This study examined the validity of the clinical tenet that poststroke recovery of the upper extremity is less rapid and complete than poststroke recovery of the lower extremity. Previous studies comparing upper and lower extremity recovery have evaluated disability rather than motor impairment. Individuals with lower extremity impairments may be more functional and appea...

BACKGROUND The clinical consequences of whiplash injuries resulting from a motor vehicle accident (MVA) are poorly understood. Thereby, there is general lack of research on the development of disability in patients with acute and chronic Whiplash Associated Disorders. METHODS/DESIGN The objective is to describe the design of an inception cohort study with a 1-year follow-up to determine risk ...