BACKGROUND Previous studies found that patients with depressive disorders frequently have lifetime manic symptoms or even an unrecognized bipolar disorder and that these patients have more severe illness. In this study we investigated whether the presence of significant manic symptoms among patients presenting with depressive and/or anxiety disorders is associated with more severe illness, more...

the aim of this study was to determine the prevalence rate of mental disorders among people aged 15 and over. after a pilot study for estimating the sample size, 625 subjects were selected by random cluster sampling from family information files in sowmaesara health centre office. in this study, ghq-28 was used as a screening tool, and dsm-iii-r clinical interview checklist for diagnostic inter...

BACKGROUND Numerous studies have observed that offspring of bipolar parents manifest a broad spectrum of psychiatric disorders. We tested the hypothesis that in high risk offspring, bipolar disorder evolves in a predictable clinical sequence from non-specific (non-mood) to specific (mood) psychopathology. METHODS Offspring from well-characterized families with one bipolar parent (high risk) o...

Poor mental health and substance use are associated with food insecurity, however, their potential combined effects have not been studied. This study explored independent associations and effect modification between lifetime substance use and mood disorder in relation to food insecurity. Poisson regression analysis of data from British Columbia respondents (n = 13,450; 12 years+) in the 2007/08...