OBJECTIVES/HYPOTHESIS To determine speech, eating, aesthetics, social disruption, and overall quality-of-life outcomes over a year period in patients who underwent transoral robotic surgery as part of carcinoma of unknown primary diagnosis and treatment. STUDY DESIGN Observational prospective study. METHODS Twenty-two patients who underwent transoral robotic surgery for the management of ca...

OBJECTIVE To assess the progression of mucopolysaccharidosis II in 11 Brazilian patients over a 12-month period. METHODS Eleven Brazilian patients with mucopolysaccharidosis II were prospectively studied at the Division of Medical Genetics of Hospital de Clínicas de Porto Alegre. The initial assessment and the assessment at 12 months included: anamnesis, physical examination, abdominal nuclea...

Background: Atrial fibrillation (AF) is an arrhythmia with complex pathophysiological characteristics. The efficiency of various anti-tachyarrhythmic stimulation algorithms in patients with recurrent AF has become a subject of research and the aim of this analysis is to evaluate the success of treatment by continuous DDD(R) stimulation with an anti-tachyarrhythmic pacing algorithm in patients w...

The study was set up to assess the completeness of reporting different types of work-related health events through 6 month and 1 week diaries and telephone questionnaires relating to individual days. Subjects recruited from hospital asthma or diabetic clinics or from surgical day-case units were randomly assigned to either a full participation arm or to one completing only a 6 month diary. Of t...

Human infants appear to be capable of the rudimentary mathematical operations of addition, subtraction, and ordering. To determine whether infants are capable of extracting ratios, we presented 6-month-old infants with multiple examples of a single ratio. After repeated presentations of this ratio, the infants were presented with new examples of a new ratio, as well as new examples of the previ...

The clinical efficacy of one or two intravitreal injections of a continued deliverance dexamethasone 700 μg implant in ten patients with persistent macular edema following uncomplicated phacoemulsification was evaluated. Complete ophthalmological examination and spectral domain optical coherence tomography were carried out. Follow-up was at day 7 and months 1, 2, 4, 6, 8, and 12. At baseline me...

INTRODUCTION Pharmaco-economic data on the management of knee osteoarthritis (OA) with intra articular hyaluronic acid (IA HA) viscosupplementation is limited. We contrasted IA HA with non-steroidal anti-inflammatory drugs (NSAIDs). METHODS Observational, prospective and multicenter study comparing treatments of knee OA costs and efficacy with either NSAIDs alone, or hyaluronic acid (Arthrum ...