Mike Levine is at the University of California, Berkeley where he is coDirector of the newly formed Center for Integrative Genomics. He obtained his Ph.D. from Yale University with Alan Garen studying steroid-regulated gene expression in Drosophila larvae. As a Jane Coffin Childs fellow he did postdoctoral research with Walter Gehring at the University of Basel in 1982. After a second short pos...

Although studies have established that exogenous growth hormone (GH) treatment stimulates growth in fish, its effects on target tissue gene expression are not well characterized. We assessed the effects of Posilac (Monsanto, St. Louis, MO), a recombinant bovine GH, on tissue transcript levels in rainbow trout selected from two high-growth rate and two low-growth rate families. Transcript abunda...

Data from the same 138 New York dairy farms for the years 1994 through 1997 were used to estimate whether Bovine Somatotropin (bST) generated profits for adopters. Data from these same farms from 1993 were used to sort farms into groups by production per cow, profit per cow, and farm size, in order to test bST response by these delineators. Statistically, farms that used bST on average experien...

Faculty who had presented at the symposium “Heart Healthy Omega-3s (n-3 fatty acids) for Food: Stearidonic Acid (SDA) as a Sustainable Choice” met and agreed upon conclusions and recommendations that could be made on the basis of evidence provided at the symposium. The participants also submitted manuscripts relating to their topics and these are presented in this supplement. These manuscripts ...

Abstract First described by the Heidelberg dermatologist Siegfried Bettman in 1897 as an occupational disease chemical workers cleaning out towers filled with hydrochloric acid, chloracne—not a true acne, despite showing comedones, cysts and pustules, but manifestation of systemic poisoning halogenated aromatic compounds—has been subject several controversial environmental disasters for over ce...

A enzyme inhibitors used in agriculture, glyphosate (N-phosphomethyl glycine) is remarkable. A nonselective herbicide discovered in 1970 by a group of scientists at Monsanto led by Dr. John Franz (1), glyphosate, since first commercialization under the trade name Roundup, has been used globally as a safe and effective means of weed control. The discovery of glyphosate’s herbicidal activity was ...

Acetyl coenzyme A synthase/carbon monoxide dehydrogenase (ACS/CODH) is a bifunctional enzyme present in a number of anaerobic bacteria. The enzyme catalyzes two separate reactions namely, the reduction of atmospheric CO2 to CO (CODH activity at the C-cluster) and the synthesis of acetyl coenzyme A (ACS activity at the A-cluster) from CO, CH3 from a corrinoid iron-sulfur protein, and the thiol c...