Rectangular hyperbolic type 2 (RHt2; Michaelis-Menten or Monod-like) functions are commonly used to describe predation kinetics in plankton models, either alone or together with a prey selectivity algorithm deploying the same half-saturation constant for all prey types referenced to external prey biomass abundance. We present an analysis that indicates that such descriptions are liable to give ...

The same processes that permit cellular control of metabolism also provide the means of regulating how genes are expressed. At the metabolic level, cellular compounds bind to specific enzymatic proteins, changing their shape and therefore their function. At the level of mRNA synthesis, a similar series of allosteric controls (enzymes) exists, regulating which genes are transcribed and to what e...

The Monod-Wyman-Changeux (MWC) model was conceived in 1965 to account for the signal transduction and cooperative properties of bacterial regulatory enzymes and hemoglobin. It was soon extended to pharmacological receptors for neurotransmitters and other macromolecular entities involved in intracellular and intercellular communications. Five decades later, the two main hypotheses of the model a...

In a summary of the general conclusions of a 1961 Cold Spring Harbor Symposium, Monod and Jacob comment that “it is obvious from the analysis of these [bacterial genetic regulatory] mechanisms that their known elements could be connected into a wide variety of ‘circuits’ endowed with any desired degree of stability” [1]. It is remarkable that now, nearly 40 years later, with near universal acce...

Risk-based assessment methods are commonly used at the contaminated sites by hydrocarbon pollutants. This paper presents the results of a two-dimensional finite volume model of reactive transport of biodegradable BTEX which have been developed for the saturated zone of an unconfined aquifer in the Pump station area of Tehran oil refinery, Iran. The model governing equations were numerically sol...

We present a simple mathematical model for the synthesis of extracellular proteins by a class of bacteria which secrete significant quantities of this exoprotein in late-exponential and stationary phases. This model is the simplest generalization of Michaelis-Menten kinetics (the Monod model) and agrees well with laboratory experiments in batch culture. The model may serve as a simple prototype...

15-P035 Molecular analysis of the architecture and the development of the peripheral nervous system of the annelid Platynereis dumerilii Pierre Kerner, Julien Béhague, Elena Simionato, Martine Le Gouar, Guillaume Balavoine, Michel Vervoort Programme Development and Neurobiology, Institut Jacques Monod, UMR 7592 CNRS/Université Paris Diderot – Paris 7, 15 rue Hélène Brion, 75205 Paris Cedex 13, ...

15-P035 Molecular analysis of the architecture and the development of the peripheral nervous system of the annelid Platynereis dumerilii Pierre Kerner, Julien Béhague, Elena Simionato, Martine Le Gouar, Guillaume Balavoine, Michel Vervoort Programme Development and Neurobiology, Institut Jacques Monod, UMR 7592 CNRS/Université Paris Diderot – Paris 7, 15 rue Hélène Brion, 75205 Paris Cedex 13, ...