In this work, a new extraction method termed aerosol phase extraction has been developed for the first time. The new method was based on the nebulisation of the sample onto the extracting solution to maximize the contact surface. The influential parameters are: agitation time, chelating agent concentration and inorganic acid concentration. The method has been applied to the extraction of molybd...

Molybdenum(V) e.p.r. spectra from reduced forms of aldehyde oxidase were obtained and compared with those from xanthine oxidase. Inhibited and Desulpho Inhibited signals from aldehyde oxidase were fully characterized, and parameters were obtained with the help of computer simulations. These differ slightly but significantly from the corresponding parameters for the xanthine oxidase signals. Rap...

Human molybdenum cofactor deficiency is a rare and devastating autosomal-recessive disease for which no therapy is known. The absence of active sulfite oxidase-a molybdenum cofactor-dependent enzyme-results in neonatal seizures and early childhood death. Most patients harbor mutations in the MOCS1 gene, whose murine homolog was disrupted by homologous recombination with a targeting vector. As i...

Essentially all organisms depend upon molybdenum oxidoreductases which require a molybdopterin cofactor for catalytic activity. Mutations resulting in a lack of the cofactor show a pleiotropic loss of molybdoenzyme activities and thereby define genes involved in cofactor biosynthesis or utilization. In prokaryotes, two operons are directly associated with biosynthesis of the pterin moiety and i...

Sucrose hydrogenolysis is industrially important for the production of polyols. To provide high glycerol yield under milder reaction conditions, a nickel catalyst promoted by Molybdenum and copper supported on kieselguhr was synthesized and optimized using Response Surface Methodology. A 3X5 experimental design has been adopted to study the effect of these constituents. A linear second-order mo...

In this paper, the influence of Ca2+ on the flotation of a skarn type molybdenum ore and pure molybdenite mineral at pH 8 was studied using diesel as the collector. It was found that Ca2+ had little effect on molybdenum flotation at low concentrations. By further increasing Ca2+ concentration, the floatability of molybdenite—especially from the fine size fractions—was depressed even without the...

The synthesis of novel biornimetic molybdenum and tungsten compounds that are potential model complexes for molybdenum and tungsten oxidase enzymes is being pursued. Model complexes such as these provide a bener understanding of the basic chemistry of a metal center in an environmeot similar to that found in particular enzyme active sites. This understanding provides a good Starting point [or b...

The detection of specific DNA sequences plays a critical role in the areas of medical diagnostics, environmental monitoring, drug discovery and food safety. This has therefore become a strong driving force behind the ever-increasing demand for simple, cost-effective, highly sensitive and selective DNA biosensors. In this study, we report for the first time, a novel approach for the utilization ...

We report the results of operation of Alcator C-Mod with all high-Z molybdenum Plasma Facing Component (PFC) surfaces. Without boron-coated PFCs energy confinement was poor (HITER,89 ~ 1) due to high core molybdenum (nMo/ne 0.1%) and radiation. After applying boron coatings, nMo/ne was reduced by a factor of 10-20 with HITER,89 approaching 2. Results of between-discharge boronization, localized...

This work gives an overview of the recent achievements which have contributed to the understanding of the structure and function of molybdenum and tungsten enzymes. Known structures of molybdo-pterin cofactor-containing enzymes will be described briefly and the structural differences between representatives of the same and different families will be analyzed. This comparison will show that the ...