M otor neurone disease includes a heterogeneous group of disorders with motor neurone involvement, such as amyotrophic lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, and primary lateral sclerosis. Amyotrophic lateral sclerosis is the most common adult onset form of motor neurone disease and involves the lower and upper motor neurones. It is characterised by progressi...

Swimming performance achieved in 50-m, 100-m and 200-m events each swimming stroke can have an influence on the final individual medley (IM) events. We attempted to quantify relative contributions of top-10 world ranked IM competition performance. examined results swimmers (90 males 90 females) between 2012 2018. A general linear model was developed examine association 400-mIM predictor variabl...

Insulin receptor tyrosine kinase substrate p53 (IRSp53) has been identified as an SH3 domain-containing adaptor that links Rac1 with a Wiskott-Aldrich syndrome family verprolin-homologous protein 2 (WAVE2) to induce lamellipodia or Cdc42 with Mena to induce filopodia. The recruitment of these SH3-binding partners by IRSp53 is thought to be crucial for F-actin rearrangements. Here, we show that ...

Understanding the interactions of humid air with ionic liquids (ILs) is critical for predicting how their physicochemical properties are affected by water. Using experimental and theoretical techniques, water vapor's interaction with aerosolized nanoparticles and thin films of [C(2)MIM][Cl] and [C(2)MIM][BF(4)] was studied. Solutions were electrosprayed to produce dry particles. Particles' hygr...

Masked image modeling (MIM) has been proved to be an optimal pretext task for self-supervised pretraining (SSP), which can facilitate the model capture effective task-agnostic representation at step and then advance fine-tuning performance of various downstream tasks. However, under high randomly masked ratio MIM, scene-level MIM-based SSP is hard small-scale objects or local details from compl...

Coherence between different surface plasmon polariton (SPP) modes excited by inelastically tunneling electrons in biased metal–insulator–metal tunnel junctions (MIM-TJs) is demonstrated. By employing a dedicated SPP stripe waveguide with MIM-TJ, an effective double-slit configuration similar to the Young's experiment realized for electrically source. The spatial correlation originates from sing...

Abstract The results of a direct numerical simulation are presented which describe the specific process porous medium high-temperature siliconizing. calculations were performed taking into account diffusion, weak pressure gradient across workpiece and heat release during condensation gaseous silicon in pores. Phenomenological formulas for evaporation coefficients dependence on temperature offer...

The phase separation of ionic liquids (ILs) in water is studied by laser light scattering (LLS). For the ILs with longer alkyl chains, such as [C(8)mim]BF(4) and [C(6)mim]BF(4) (mim = methylimidazolium), macroscopic phase separation occurs in the mixture with water. LLS also reveals the coexistence of the mesoscopic phase, the size of which is in the order of 100-800 nm. In aqueous mixtures of ...

OBJECT The safe integration into practice of a new surgical technique requires an appreciation of the learning curve. The object of this study was to assess the learning curve for minimally invasive microdiscectomy (MIM) utilizing a tubular retractor system. METHODS A prospective evaluation of a single surgeon's first 52 consecutive MIM cases for radiculopathy secondary to single-level poster...

Between the metal–insulator–metal (MIM) capacitor and metal–oxide–metal (MOM) capacitor, the MIM capacitor has a better characteristic of stable capacitance. However, the MOM capacitors can be easily realized through the metal interconnections, which does not need additional fabrication masks into the process. Moreover, the capacitance density of the MOM capacitor can exceed the MIM capacitor w...