Overactive mitochondrial fission was shown to promote cell transformation and tumor growth. It remains elusive how mitochondrial quality is regulated in such conditions. Here, we show that upregulation of mitochondrial fission protein, dynamin related protein-1 (Drp1), was accompanied with increased mitochondrial biogenesis markers (PGC1α, NRF1, and Tfam) in breast cancer cells. However, mitoch...

Fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after physical activity. Etiologic mechanisms underlying fatigue are not well understood; however, fatigue is a hallmark symptom of mitochondrial disease, making mitochondrial dysfunction a putative biological mechanism for fatigue. Therefore, this review examin...

Abstract We analysed data on nucleotide polymorphism at 78 nuclear genes to search for signatures of divergence and selection in populations from across the distribution Pinus sylvestris Europe. Data variation a large set maternally inherited mitochondrial DNA markers were also analysed. Most loci showed homogeneous patterns Spain, Central Europe, Nordic countries Scotland. Mitochondrial did no...

Spiders of the genus Cybaeus L. Koch, 1868 exhibit two major centers diversity: Western North America and Japan. Several Japanese possess an elongated embolus in male palp tubular spermathecae female genitalia. Here we describe koikei sp. nov. from central Honshu, Japan, which has unelongated bulbous spermathecae. Phylogenetic analyses using nuclear mitochondrial gene markers clearly support mo...

A genetic assessment was done on the greenblotch parrotfish (Scarus quoyi Valenciennes, 1840) in three bays within southern Mindanao, Philippines. Mitochondrial 16S rRNA recovered 12 haplotypes, one of which dominant all sites. Despite reported phenotypic variation from previous assessments, there neither evidence structure (global Φst = 0.012, p 0.13) nor isolation by distance (r 0.05, 0.50). ...

The Woodland Kingfisher Halcyon senegalensis is widely distributed throughout sub-Saharan Africa and occupies a wide variety of woodland savannah habitat. Thus far, three subspecies have been described based on morphological variation. In the present study, using western, eastern southern African populations, we examined relationship between genetic divergence among two named subspecies, H. s. ...

A new species of damselfish, Altrichthys aleliasp. n. is described from specimens collected in shallow water (1-8m depth) off Busuanga Island, Palawan Province, Philippines. It differs from the other two species in the genus, A. curatus and A. azurelineatus, in various features including having golden upper body lacking dark edges of dorsal and caudal fins, higher modal number of tubed lateral ...

Conservation policy in the giant Galápagos tortoise, an iconic endangered animal, has been assisted by genetic markers for ~15 years: mitochondrial DNA and microsatellite loci have been used to delineate thirteen (sub)species, between which hybridization is prevented. Here, comparative reanalysis of a previously published NGS data set reveals a conflict with traditional markers. Genetic diversi...

Cytoplasmic inheritance was investigated in interspecific hybrids of Wisteria sinensis and W. floribunda. Species-specific nuclear, mitochondrial and plastid DNA markers were identified from wild-collected plants of each species in its native range. These markers provide evidence for the bi-parental transmission of plastids in hybrid swarms of these two species in the southeastern USA. These po...

The taxonomic status of Thamnurgus rossicus was evaluated with respect to the morphologically similar T. petzi using genetic markers. Nucleotide data from the mitochondrial COI gene revealed 2.4% variation between the European Alps and Russian steppe populations. The two nuclear DNA markers CAD and EF1á were identical across populations. In view of their similar morphology, genetic composition,...