نتایج جستجو برای: mir 144

تعداد نتایج: 59358  

2006
Shyamala C. Doraisamy Hamdan Adnan Noris Mohd. Norowi

Systems for the archival of musical documents digitally and development of digital music libraries are currently being researched and developed extensively. However, adapting these systems for the archival and retrieval of Malaysian music materials might not be as straightforward due to the distinct differences in musical structure and modes of non-Western music. This paper covers the motivatio...

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری 1393

سرطان مری ششمین عامل مرگ و میرهای ناشی از سرطان در دنیا می باشد. استان گلستان در شمال شرقی ایران یکی از قطب¬های جهانی با شیوع بالای سرطان مری از نوع کارسینومای سلول سنگفرشی (escc) محسوب می¬شود. مکانیسم¬های مولکولی دخیل در این بیماری هنوز بطور دقیق شناخته نشده است. اخیرا نقش mirnaها در پاتوژنز سرطانها نشان داده شده است. در این تحقیق، پروفایل بیانی بیش از هفتصد mirna در نمونه¬های بافتی پارافینه ک...

Journal: :Oncology reports 2013
Angelika Tölle Monika Jung Silke Rabenhorst Ergin Kilic Klaus Jung Steffen Weikert

Since differential expression of microRNAs (miRNAs) has been found to be highly associated with several types of cancer, the goal of the present study was to identify an miRNA fingerprint as a non‑invasive diagnostic tool to detect urinary bladder cancer using the easily accessible samples of whole blood and urine. Blood and urine samples from 4 controls and from patients suffering from superfi...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2012
Katerina Vaporidi Eleni Vergadi Evangelos Kaniaris Maria Hatziapostolou Eleni Lagoudaki Dimitrios Georgopoulos Warren M Zapol Kenneth D Bloch Dimitris Iliopoulos

The aim of this study was to investigate the changes induced by high tidal volume ventilation (HVTV) in pulmonary expression of micro-RNAs (miRNAs) and identify potential target genes and corresponding miRNA-gene networks. Using a real-time RT-PCR-based array in RNA samples from lungs of mice subjected to HVTV for 1 or 4 h and control mice, we identified 65 miRNAs whose expression changed more ...

2016
Hui Cai Jiping Xu Yifang Han Zhengmao Lu Ting Han Yibo Ding Liye Ma

PURPOSE This study aimed to identify molecular prognostic biomarkers for gastric cancer. METHODS mRNA and miRNA expression profiles of eligible gastric cancer and control samples were downloaded from Gene Expression Omnibus to screen the differentially expressed genes (DEGs) and differentially expressed miRNAs (DEmiRs), using MetaDE and limma packages, respectively. Target genes of the DEmiRs...

2012
Cristina Girardi Cristiano De Pittà Silvia Casara Gabriele Sales Gerolamo Lanfranchi Lucia Celotti Maddalena Mognato

BACKGROUND Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathway can originate from alteration in the functionality of the microRNA-mediated gene regulation, being microRNAs (miRNAs) small noncoding RNA that act as post-transcriptional regulators of gene express...

2017
Ze-Min Yang Long-Hui Chen Min Hong Ying-Yu Chen Xiao-Rong Yang Si-Meng Tang Qian-Fa Yuan Wei-Wen Chen

Type 2 diabetes mellitus (T2DM) is characterized by islet β-cell dysfunction and insulin resistance, which leads to an inability to maintain blood glucose homeostasis. Circulating microRNAs (miRNAs) have been suggested as novel biomarkers for T2DM prediction or disease progression. However, miRNAs and their roles in the pathogenesis of T2DM remain to be fully elucidated. In the present study, t...

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