Background and Objective: Ulcerative colitis (UC) is an unknown recurrent intestinal disease and a common cause of gastrointestinal disorders, which may lead to colorectal cancer if not diagnosed and treated in a timely manner. The beneficial effects of several probiotics in diseases like inflammatory bowel disease (IBD) have been investigated, although their mechanisms have not been yet fully ...

Background: Gastric cancer is among the most common malignancies in certain parts of the world, such as northwest Iran. miRNAs are small and single-stranded noncoding RNAs with about 19-23 nucleotides. Several studies have shown that miRNAs play important roles in gastric tumorigenesis. The aim of this study was to determine the effect of miRNA-1266-5p repression on the cell survival and altera...

A local luminosity function at 15µm is derived using the bivariate (15µm vs. 60µm luminosity) method, based on the newly published ISOCAM LW3-band (15µm) survey of the very deep IRAS 60µm sample in the north ecliptic pole region (NEPR). New IRAS 60µm fluxes are obtained using the SCANPI/SUPERSCANPI software at the new ISOCAM positions of the sources in the sample. It is found to be in excellent...

Abstract Esophageal cancer (EC) including esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) generally exhibits poor prognosis; hence, a noninvasive biomarker enabling early detection is necessary. Age- sex-matched 150 healthy controls (HCs) 43 patients with ESCC were randomly divided into two groups: 9 individuals in the discovery cohort for microarray analysis 184 training/tes...

Abstract Chronic kidney disease (CKD), characterized by progressive loss of function, is a major cause mortality in cats. Another complication the formation calcium oxalate (CaOx) uroliths bladder and kidneys cats, where inflammation has role its pathogenesis. MicroRNAs (miRNAs) are small non-coding RNAs which bind to target mRNA reduce function. Depending on mRNA, they regulate transcription s...

Objective(s): Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI). This study aimed to investigate the effect and the molecular basis of miR-103 on LPS-induced injuries in PC12 cells in vitro and SCI rats in vivo. Materials and Methods: PC12 cells were exposed to LPS to induce cell injuries to mimic the in ...

Bladder cancer is the second most common cancer in the genitourinary tract, showing often recurrence and progresse into invasive states. Epigenetic changes, such as microRNA alteration are involved in bladder cancer tumorigenesis through a variety of signaling pathways. The epigenetic state depends on geographic and lifestyle conditions. The aim of this study was to investigate the expression l...