This paper proposes an optical surface reconstruction method from multiview projectional data acquired by a multimodality imaging instrumentation. The technique is adapted for in vivo small animal imaging, specifically imaging of nude mouse in the case where the influence of CT radiation doses should be eliminated. Any potential point within the field-of-view (FOV) of a nude mouse is evaluated ...

Regulation of calcitonin (CT)/calcitonin gene-related peptide (CGRP) RNA processing involves the use of alternative 3' terminal exons. In most tissues and cell lines, the CT terminal exon is recognized. In an attempt to define regulatory sequences involved in the utilization of the CT-specific terminal exon, we performed deletion and mutation analyses of a mini-gene construct that contains the ...

Considering the general application of dedicated small-animal positron emission tomography/computed tomography is limited, an acceptable alternative in many situations might be clinical PET/CT. To estimate the feasibility of using clinical PET/CT with [F-18]-fluoro-2-deoxy-D-glucose for high-resolution dynamic imaging and quantitative analysis of cancer xenografts in nude mice. Dynamic clinical...

Materials and Methods: Nine canine models of left anterior descending artery stenosis were prepared and underwent MDCT perfusion imaging during adenosine infusion to study a wide range of flow parameters. Neutron-activated microspheres were injected to document MBF during adenosine infusion. Six animals underwent dynamic MDCT perfusion imaging, and K1 and k2 (which represent the first-order tra...

Molecular imaging technique is an attractive tool to detect liver disease at early stage. This study aims to develop a simultaneous dual-isotope single photon emission computed tomography (SPECT)/CT imaging method to assist diagnosis of hepatic tumor and liver fibrosis. Animal models of liver fibrosis and orthotopic human hepatocellular carcinoma (HCC) were established. The tracers of (131)I-NG...

Epidermal growth factor receptor mutant III (EGFRvIII) is exclusively expressed in tumors, such as glioblastoma, breast cancer and hepatocellular carcinoma, but never in normal organs. Increasing evidence suggests that EGFRvIII has clinical significance in glioblastoma prognosis due to its enhanced tumorigenicity and chemo/radio resistance, thus the development of an imaging approach to early d...

Background: X-ray computed tomography (CT) examinations deliver a significant amount of radiation doses to patients comparing to conventional radiography examinations. The objective of the current study was to analyze and investigate the average patient received dose from axial and spiral CT exams in a medical imaging center. Material and Methods: In this study, the patient imaging tec...

INTRODUCTION The purposes of this study were to determine the ideal sites for placement of orthodontic mini-implants in mandibular interradicular spaces by using computed tomography (CT) and to suggest length, diameter, and angulation of the mini-implants. METHODS CT scans were performed on 15 dry human mandibles with 1-mm tomography slices. Measurements were made at 3, 5, 7, 9, and 11 mm hei...