Bilateral middle ear congenital cholesteatoma (CC) is an extremely rare disease. Middle ear CC grows from birth behind the intact ear drum, with no symptoms. Usually, it is detected by the pediatrician at the time of a routine visit. Undetected, it may grow for years until becoming quite large. Etiology of middle ear CC is still controversial, but it seems that an embryologic origin is the most...

OBJECTIVE To determine whether there is an association between otitis media with effusion and laryngopharyngeal reflux in children. MATERIALS AND METHODS This study included 31 children with otitis media with effusion. The pepsinogen level in the middle ear fluid of all patients was measured by sandwich enzyme-linked immunosorbent assay. Each patient's middle ear fluid was investigated for He...

otitis media with effusion (ome) is very common in pediatric patients. immune reactions in serum and middle ear system play roles in the etiology, pathogenesis and prevention of otitis media. immunologically active antigens interact with immunocompetent cells in the lamina propria of the middle ear to produce a local immune response. in this investigation, 32 sera and 50 middle ear fluid sample...

The 41 papers that compose this volume were presented at the McCollumPratt Institute Symposium in the spring of 1958. They fall into four broad categories entitled Developmental Cytology, Cellular and Tissue Interactions in Development, Problems of Specificity in Development, and Control Mechanism in Development. Many of the current leaders in developmental biology contribute to the book either...

M odern industry has produced a noisy world. The din of jack­ hammers, the whine of jet engines and the blare of amplified electric guitars have become all too commonplace. It was therefore con­ siderate of nature to have equipped the human ear with a rather sophis­ ticated noise-reduction system: two small muscles that are attached to the ossicles, the tiny bones that connect the eardrum to th...