background: hyperlipidemia and oxidized-low-density lipoproteins (ox-ldl) are important independent cardiovascular risk factors that have been shown to stimulate vascular smooth muscle cell (vsmc) proliferation. the purpose of the present study was to investigate the effect of vitamin e on ox-ldl, lipid profile, c-reactive protein (crp), and vsmc proliferation of rat aorta. methods: male wistar...

objective(s) the use of co-culture cells as well as extra cellular matrix are among those strategies that have been employed to direct mesenchymal stem cell (msc) bone differentiation in culture. in this regard, there is no study considering the effects of matrigel on mesenchymal stem cell (msc) in vitro bone differentiation. this was the subject of the present study. materials and methods huma...

bordetella pertussis infects the respiratory tract of the human host and causes whooping cough in children. the nature of immunity against bordetella pertussis infection and disease is poorly understood. the aim of this study was to investigate cell mediated immunity in mice immunized with outer membrane component of cell wall, of b. pertussis. a group of mice were immunized with outer membrane...

mobile phone use and wireless communication technology have grown explosively over the past decades. this rapid growth has caused widespread global concern about the potential detrimental effects of this technology on human health. stem cells generate specialized cell types of the tissue in which they reside through normal differentiation pathways. considering the undeniable importance of stem ...

objective: osteoporosis or silent disease is a major bone disorder in elderly women in current century. estrogen has an important role in osteogenesis and prevention of bone fractures. hormone replacement therapy (hrt) is usually accompanied by such effects as breast and ovary cancers. thus, there is an increasing demand for replacement with plant phytoestrogens. this study is focused on determ...

in this study cellular phosphatase activity, referred to as enzyme developed color (edc) assay, was used for an in vitro assessment of cell proliferation and cytotoxicity. optimum conditions were established and found to be 10 x103 cells / well at 37°c and 60 min incubation (for developing color). under the same conditions a direct correlation between optical density (00) and cell number was ob...

objective: this study presents an efficient, cost-effective method to improve proliferation and colonization of spermatogonial stem cells (sscs) in vitro. methods: isolated sscs from neonate mice were cultured in dmem culture medium with 10% fetal bovine serum (fbs). in the first phase of the study, the temperature was controlled by low intensity pulsed ultrasound stimulation (lipus) of the pla...

the number of vegetable processing plants has been increased during recent years in iran as many other countries. on the other hand, fresh vegetable products are susceptible to microbial contamination after harvest, processing, handling, packing and distribution. the aim of this study was to determine and evaluate the level of microbial load of vegetables during different cleaning steps in a fr...

The antimicrobial peptide LL-37 not only contributes to the host defence against microbial invasion but also regulates immune activity, angiogenesis and cell proliferation. Studies have shown that LL-37 participates in the development of a variety of tumours, such as lung cancer, ovarian cancer, breast cancer and melanoma. However, the role of LL-37 in the development of skin squamous cell carc...