Cytomegalovirus (CMV), a betaherpesvirus, causes significant human morbidity and mortality. It is present in at least 60% of the US population [1], with a prevalence of 90% in high-risk groups, including men who have sex with men [2, 3]. In immunocompetent hosts, CMV infection is usually asymptomatic, but it persists throughout an individual’s lifetime and has the potential to reactivate and ca...