BACKGROUND Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediately precede the initiation of depot typical antipsychotics in the usual treatment of schizophrenia patients with a recent history of nonadherence with oral antipsychotic regimens....

Glucocorticoids promote fat accumulation in visceral compared to subcutaneous depots, but the molecular mechanisms involved remain poorly understood. To identify long-term changes in gene expression that are differentially sensitive or responsive to glucocorticoids in these depots, paired samples of human omental (Om) and abdominal subcutaneous (Abdsc) adipose tissues obtained from obese women ...

The vehicle routing with pickups and deliveries (VRPD) problem is de6ned over a graph G=(V; E). Some vertices in G represent delivery customers who expect deliveries from a depot, and other vertices in G represent pickup customers who have available supply to be picked up and transported to a depot. The objective is to 6nd a minimum length tour for a capacitated vehicle, which starts at a depot...

The adrenocorticotrophic effects of a synthetic corticotrophin analogue, alpha(1-18) ACTH with D-serine(1), lysine(17), and lysine amide(18) substitutions has been studied. It is effective after both intramuscular and subcutaneous administration and compared with tetracosactrin depot (Synacthen depot, Cortrosyn depot) it has a similarly prolonged time course of action-about 24 hours after 0.5 m...

OBJECTIVE Nonadherence is a major challenge in schizophrenia treatment. While long-acting (depot) antipsychotic medications are often recommended to address adherence problems, evidence on the comparative effectiveness of depot versus oral antipsychotics is inconsistent. We hypothesize that this inconsistency could be due to systematic differences in study design. This review evaluates the effe...

*Correspondence: Alfredo Mahar F. Lagmay, National Institute of Geological Sciences, University of the Philippines Diliman, P.Velasquez Street, Diliman, Quezon City 1101, Metro Manila, Philippines e-mail: [email protected]; [email protected] Many volcanoes worldwide are located near populated cities that experience monsoon seasons, characterized by shifting winds each year. Because...

Traffic-related pollutants have been reported to increase the morbidity of respiratory diseases. In order to apply management policies related to motor vehicles, studies of the floating population living in cities are important. The rate of metro rail transit system use by passengers residing in Seoul is about 54% of total public transportation use. Through the rate of metro use, the people-flo...

This paper provides new evidence on the link between airline tra±c and employment in a metro area. The evidence con ̄rms the common view that good airline service is an important factor in urban economic development. Frequent service to a variety of destinations, re°ected in a high level of passenger enplanements, facilitates easy face-to-face contact with businesses in other cities, attracting ...

Metro Ethernet has recently attracted remarkable attention due to its simplicity and low cost. Although Ethernet is the dominant technology in the Local Area Network (LAN) which usually handles small number of nodes, when deploying in Metropolitan Area Networks (MANs), it faces certain challenges. One major challenge is its broadcasting based address resolution scheme. A broadcast-based address...

This paper deals with a real-life vehicle delivery routing problem, which is a seafood product delivery routing problem. Considering the features of the seafood product delivery routing problem, this paper formulated this problem as a multi-depot open vehicle routing problem. Since the multi-depot open vehicle routing problem is a very complex problem, a method is used to reduce the complexity ...