The anti scorpion venom activity of the Indian medicinal plant (Hemidesmus indicus, Pluchea indica and Aristolochia indica) root extracts (aqueous and methanol) was established in experimental animal models. Adult black scorpions (Heterometrous bengalensis) of both sexes were collected and the Scorpion Venom (SV) was collected by electrical stimulation, pooled, lyophilized and stored at 4 °C. S...

The venom of the South African scorpion Parabuthus transvaalicus was characterized using a combination of mass spectrometry and RP-HPLC separation and bioassays. The crude venom was initially separated into 10 fractions. A novel, moderately toxic but very high abundance peptide (birtoxin) of 58 amino-acid residues was isolated, identified and characterized. Each purification step was followed b...

b a ckground : scorpion sting is a major health problem in iran. the aim of current study was to measure the inci- dence rates of scorpion stings, mortality, recovery, and affected age groups. the results of treatment with and with out anti venom also were considered in the entire country during 2009 . m e t hods: all the data were collected from emergency section of different hospitals and the...

Background The epidermal growth factor (EGF) is recognized medicine of therapy in ulcer. However, its efficacy has been challenged. We compared scorpion venom active polypeptide and EGF of therapeutic effects in diabetic ulcer. Methods The scorpion venom active polypeptide is made into gel. Fourteen diabetic SD rats were randomly divided into scorpion peptide gel group (SPG group) and EGF gro...

The novel insecticidal toxin, LaIT2, was isolated from venom of the scorpion Liocheles australasiae. The amino acid sequence of LaIT2 was determined by an Edman degradation analysis and subsequent cDNA cloning. LaIT2 is composed of 59 amino acids with three disulfide bridges, and shares sequence similarity to the scorpion beta-KTx peptides.

Scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the Middle East. In Iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from Khuzestan province. Among the 21,000 cases of reported scorpion stung patients, 12% were caused by H. lepturus, but contributed to 95% of all moralities in ...

INTRODUCTION Complications following scorpion sting are common in India and can be fatal. Stroke following scorpion sting is a rare complication and can occur by various mechanisms such as hypertension, hypotension, DIC, myocarditis and venom-induced vasculitis. We present a rare case of extensive cerebellar infarction following scorpion sting, which has rarely been reported in medical literatu...

The constituents of scorpion venom have not yet been fully identified. During preliminary investigation of the venom of Leiurus qidnquestriatus by paper chromatography, a spot corresponding in position to that due to 5-hydroxytryptamine (HT) was seen. This paper is concerned with the methods of identification and assay of this substance in venom, and also considers the histochemistry of the ven...