background: migraine is a chronic disease that affects nearly 6% of men and 18% of women worldwide. there are various drugs, which can successfully decrease migraine symptoms and frequency of migraine attacks, but these drugs usually are expensive. hence, this study aimed to assess the effects of pyridoxine  supplementation on severity, frequency and duration of migraine attacks as well as head...


 CADTH recommends that Qulipta be reimbursed by public drug plans for the prevention of episodic migraine, if certain conditions are met.
 should only adults with according to criteria used other calcitonin gene-related peptide (CGRP) inhibitors migraine.
 In addition following pre-existing CGRP inhibitors, not in combination inhibitors. cost is reduced such total treatment does...

Migraine is a common, disabling, complex brain disorder, presenting in attacks that may have up to 3 phases: a prodromal phase, the aura phase, and the headache phase. The pathogenesis of the aura and headache phases is reasonably well understood, but the mechanism by which migraine attacks are triggered is unknown. Most likely, migraineurs have a genetically determined reduced threshold for mi...

OBJECTIVE To describe the course of migraine without aura and migraine with aura during pregnancy and factors that could influence its course, among migraine sufferers before pregnancy. METHOD A cross sectional study undertaken at the IMIP, Brazil. Out of 686 consecutively assisted women, at the first postnatal week, 266 were identified as migraine sufferers before pregnancy. RESULTS There ...

This study has evaluated depression in patients with episodic migraine (n=98), chronic migraine without medication overuse (n=23), and chronic migraine with medication overuse (n=57). The Beck Depression Inventory (BDI) was used to evaluate depressive symptoms in these three groups. The mean BDI score obtained in all patients was higher than that observed in asymptomatic subjects (episodic migr...

OBJECTIVES This study aimed to survey the headache diagnoses and consequences among outpatients attending neurological services in 8 Asian countries. METHODS This survey recruited patients who consulted neurologists for the first time with the chief complaint of headache. Patients suffering from headaches for 15 or more days per month were excluded. Patients answered a self-administered quest...

Unilateral head pain focused on frontal, orbital or parietal regions is a leading symptom of migraine attacks. Rarely, head pain in migraine can extend involving the maxillary or mandibular region of the face, sometimes isolated facial pain is the only and atypical presentation of migraine. The prevalence of these unusual symptoms in migraine is unknown. We aimed to estimate the true prevalence...

context migraine is a major dilemma and problem which affects public health and results to reduced quality of life. this study aimed to determine the prevalence of migraine in iran. evidence acquisition a systematic search was conducted using pub med, web of science, embase, scopus, ovid, google scholar, as well as iranian databases including: magiran, iranmedex and scientific information datab...

PURPOSE To investigate drug use, prescribing patterns, and comorbidities among patients with migraine in a large pharmacy claims database. METHODS 104,625 migraine subjects (identified according to the criteria in the International Classification of Diseases, Ninth Revision [ICD-9] for migraine or migraine-specific acute medication use) and an equal number of control patients were selected fr...