Following chronic daily headache, neoplastic meningitis was diagnosed in a non-smoking 44-year-old man. A bronchial adenocarcinoma was found to be the primary tumor. He was treated with erlotinib. Meningitis as the first manifestation of a malignancy is very rare.

Infectious meningeal syndromes represent a serious medical emergency whose clinical-epidemiologic diagnosis must be immediately established for early initiation of appropriate treatment. However, in many cases data from the clinical exam are insufficient to confirm or rule out the diagnosis. Therefore, the aim of this work was to assess the value of the ocular globe compression sign in 57 patie...

Two cases of meningeal invasion by non-myelomatous plasma cell dyscrasias--a plasma cell leukaemia and an extramedullary plasmacytoma--are described. Both were secretors of IgD paraprotein and both were diagnosed in life, characteristics which we have not found in any other published case of plasma cell leptomeningitis. Analysis of our patients and of another 25 cases suggests as predisposing f...

This is a report on 2 cases of plaguemeningitis observed by us among the comparatively small material of 41 instances of plague treated at Wellington, Nilgiris, in 1945-46. We consider our cases worthy of record as the cerebro-spinal type of plague has been described in very few instances only, the disease being believed to be of extreme rarity. Lewillon, Devignat and Schoetter (1940) reported ...

Aims. We report on the unusual case of a 43-year-old man who developed recurrent meningeal hemangiopericytoma and presented with hypoglycemia 6 years after excision of the tumor. Methods and Results. We utilized computed tomography to assure multiple tumor metastasis and cranial recurrence of previous meningeal hemangiopericytoma and clinical laboratory tests and immunohistochemical staining to...

Extradural meningeal cysts are rare lesions and are uncommon causes of spinal cord or nerve compression. Most of these lesions probably remain unrecognized life-long, because they cause no symptoms. With the widespread use of new imaging techniques, asymptomatic spinal extradural meningeal cysts are becoming increasingly common. The therapeutic guidelines have not been well-established yet. Gen...

BACKGROUND Neoplastic meningitis is a complication of solid and hematological malignancies. It consists of the spread of malignant cells to the leptomeninges and subarachnoid space and their dissemination within the cerebrospinal fluid. METHODS A literature review was conducted to summarize the clinical presentation, differential diagnosis, laboratory values, and imaging findings of neoplasti...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

BACKGROUND Primary meningeal melanocytoma is a rare neurological disorder. Although it may occur at the base of the brain, it is extremely rare at the anterior cranial fossa. CASE PRESENTATION A 27-year-old man presented with headache and diplopia at our department. Fundoscopy showed left optic nerve atrophy and right papilledema consistent with Foster-Kennedy syndrome. Neurological exams wer...