Infertility affects about 10-15% of all couples attempting pregnancy with infertility attributed to the male partner in approximately half of the cases. Proposed causes of male infertility include sperm motility disturbances, Y chromosome microdeletions, chromosomal abnormalities, single gene mutations, and sperm mitochondrial DNA (mtDNA) rearrangements. To investigate the etiology of decr...

BACKGROUND The prevalence of infertility is variable between 5-30% around the world. In Iran, more than 2 million couples suffer from infertility. Infertility causes depression, anxiety, social isolation and sexual dysfunction. OBJECTIVE This descriptive study was undertaken to determine general health in infertile couples. MATERIALS AND METHODS One hundred and fifty infertile couples atten...

Reduced sperm quantity and motility are primary causes of infertility in men. Before researchers showed that, Nsun7 gene has roles in sperm motility of mouse, that creation defect in this gene is cause infertility. This gene in human located in chromosome 4, with 12 exons and a hot spot exon (exon7). Our aim is study of the mutations of the exon7 in the normospermic and asthenoteratospermic men...

Background: Presence of antisperm antibodies (ASAs) in infertility and their adverse effects on fertility is a matter of controversy. The aims of this study were to determine the percentage of antibody positive sperms and rate of ASA positive sera in both fertile and infertile men and women, and to find the association between these antibodies and infertility. Methods: This study consisted of 2...

Title: Psychological distress as predictor of quality of life in men experiencing infertility: a cross-sectional survey

PURPOSE Infertility is one of the less common presenting features associated with testicular tumors. We evaluated the histologic and biochemical findings, and pregnancy outcome in patients presenting with infertility who were found to have testicular tumors. METHODS Seven patients with infertility were found to have testicular cancer over a 15-year period. All patients had a testicular ultras...

Although methylenetetrahydrofolate reductase, a folate enzyme gene, has been associated with idiopathic male infertility, few studies have examined other folate-related metabolites and genes. We investigated whether idiopathic male infertility is associated with variants in folate, vitamin B(12) (B12) and total homocysteine (tHcy)-related genes and measured these metabolites in blood. We conduc...

Introduction and Aim: Idiopathic infertility accounts for at least 30% of all cases infertility, oxidative stress has been identified as a novel developing factor in idiopathic male infertility. Oxidative occurs when antioxidant defense mechanisms are outmatched by the creation reactive oxygen species (ROS). The purpose this research was to examine impact enzymatic antioxidants (catalase supero...

BACKGROUND Several animal studies have raised concern about the risk for obstructive azoospermia owing to vasal fibrosis caused by the use of alloplastic mesh prosthesis in inguinal hernia repair. The aim of this study was to determine the prevalence of male infertility after bilateral mesh repair. METHODS In a prospective study, a questionnaire inquiring about involuntary childlessness, inve...

It has been documented that almost 50% of the infertility problems are at present attributed to male factors. In IVF centres, potential infertile men are screened for the sperm quality by semen analysis, in particular investigating concentration, motility and morphology according to WHO guidelines [1]. However, at present, these parameters appear to be poor predictors of the fertilization succe...