نتایج جستجو برای: melanocyte stimulating hormone

تعداد نتایج: 187749  

Journal: :The Journal of investigative dermatology 2011
Erzsébet Gáspár Kim T Nguyen-Thi Celine Hardenbicker Stephan Tiede Christian Plate Eniko Bodó Jana Knuever Wolfgang Funk Tamás Bíró Ralf Paus

In amphibians, thyrotropin-releasing hormone (TRH) stimulates skin melanophores by inducing secretion of α-melanocyte-stimulating hormone in the pituitary gland. However, it is unknown whether this tripeptide neurohormone exerts any direct effects on pigment cells, namely, on human melanocytes, under physiological conditions. Therefore, we have investigated whether TRH stimulates pigment produc...

Journal: :Hypertension 2015
Zhigang Shi Priscila A Cassaglia Laura C Gotthardt Virginia L Brooks

Pregnancy increases sympathetic nerve activity (SNA), but the mechanisms are unknown. Here, we investigated the contributions of the hypothalamic paraventricular and arcuate nuclei in α-chloralose-anesthetized pregnant and nonpregnant rats. Baseline arterial pressure (AP) was lower, and heart rate (HR), lumbar sympathetic activity, and splanchnic SNA were higher in pregnant rats compared with n...

Journal: :The Journal of biological chemistry 2009
Jung-hyun Lee Haein Park Heesung Chung Sojoong Choi Younghwa Kim Hyun Yoo Tae-Yoon Kim Hoo-Jae Hann Ikjoo Seong Jaesang Kim Kathleen G Kang Inn-Oc Han Eok-Soo Oh

Syndecan-2, a transmembrane heparan sulfate proteoglycan, is a critical mediator in the tumorigenesis of colon carcinoma cells. We explored the function of syndecan-2 in melanoma, one of the most invasive types of cancers, and found that the expression of this protein was elevated in tissue samples from both nevus and malignant human melanomas but not in melanocytes of the normal human skin tis...

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