Bacillus species are promising producers of various compounds that have pronounced antimicrobial, antiviral and antitumor activities. Due to its GRAS status, subtilis represents an excellent candidate for the usage in plant pathogens biocontrol. In this research, evaluation antifungal metabolites biosynthesis by ATCC 6633 optimization glycerol-based medium composition, using response surface me...

Abstract Surrogate-assisted evolutionary algorithms have been paid more and attention to solve computationally expensive problems. However, model management still plays a significant importance in searching for the optimal solution. In this paper, new method is proposed measure approximation uncertainty, which differences between solution its neighbour samples decision space, ruggedness of obje...

This paper describes optimization of fermentation conditions for the production of thermostable pullulanase from a new strain Bacillus cereus FDTA 13, isolated from tapioca soil. By using one-factor-at-a-time and orthogonal array method, a simple medium with effective and minimal components was optimized for maximal pullulanase production. The optimized medium containing (in g/L): starch 20, ye...

We discuss the mathematical aspects of wave field measurements used in traveltime inversion from seismograms. The primary information about the medium is assumed to be carried by the wave front set and its perturbation with repsect to a hypothetical background medium is to be estimated. By a convincing heuristics a detection procedure for this perturbation was proposed based on optimization of ...