Using a polyclonal antiserum a cDNA encoding a Rab escort protein (REP) homolog in Drosophila has been identified and sequenced. The gene encodes a 511 residue protein with a predicted molecular mass of 56855 Da. Antibody labeling demonstrates that Drosophila REP protein is present in the early embryo and that it is being apportioned uniformly throughout the embryo in a process likely to be lin...

Choroideremia (CHM) is an X-linked retinal degenerative disease resulting from a lack of functional Rab Escort Protein-1 (REP-1). As a first step in developing gene-based therapies for this disease, we evaluated the feasibility of delivering functional REP-1 to defective lymphocytes and fibroblasts isolated from individuals with CHM. A recombinant adenovirus delivering the full-length human cDN...

In this paper we propose to apply multi-user detection techniques to the GSM system allowing either more transmitters per cell or higher data rates for point to point communications. In this former context, a optimal maximum likelihood channel estimator is derived. To increase the robustness of the transmission, iterative receivers are proposed including channel decoding and re-estimation of th...

We describe a method for efficiently and coherently converting photons from one wavelength to another through the process of nonlinear upconversion. By using an intense 1064 nm escort laser pulse and a periodically poled lithium niobate (PPLN) crystal, we demonstrate upconversion efficiency of 99% and coherence of 95% for 1550 to 631 nm light at the single-photon level, thereby qualifying it fo...

This brief report examines whether male sex workers mentioned any health concerns in their online ads. The analysis uses 203 male escorts' online ads collected from America Online chat rooms in 2001/2002. The results indicate that only 25 percent of male escorts explicitly mentioned any health-related words or phrases in their ads. The results also show that whether a male escort mentioned heal...

We want to reveal the usefulness of mobile robots by showing concrete applications in human daily life through this study. In this paper, our trials to realize several specific tasks are shown. The development of an Intelligent Escort Robot moving together with human is presented first. A teleoperated book browsing robot is described next. And finally, a network-based stationeries rental servic...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 4 595–608 www.jcb.org/cgi/doi/10.1083/jcb.201409142 JCB 595 *L. Luo, H. Wang, and C. Fan contributed equally to this paper. Correspondence to Yu Cai: [email protected] Abbreviations used in this paper: Arm, Armadillo; Bam, bag of marbles; CB, cystoblast; ChIP, chromatin immunoprecipitation; Dally, division abnormally delayed; Dpp...