BACKGROUND/AIMS The treatment for chronic hepatitis C (CHC) is removal of the virus in order to prevent progression to liver cirrhosis and hepatocellular carcinoma (HCC). Few data have been presented regarding the clinical significance of changes in the alanine aminotransferase (ALT) level in this context. We analyzed the patterns of changes in ALT level and investigated the relationship betwee...

We tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant systems of Caenorhabditis elegans with small synthetic superoxide dismutase/catalase mimetics. Treatment of wild-type worms increased their mean life-span by a mean of 44 percent, and treatment of prematurely aging worms resulted in normalization of their life-span (a 67 percent increase). It app...

In this paper, we adopt supreme-utilities among fuzzy level (decision) vectors to propose a power allocation rule, its efficient extension and normalization in the framework of multicriteria fuzzy transferable-utility (TU) games. We also provide several axiomatic results to present the rationality for these rules. Based on different viewpoints, we introduce different formulations and dynamic re...

We show that the entire cyclic cohomology of Banach algebras defined by Connes has the simplicial normalization property. A key tool in the proof is the notion and properties of supertraces on the Cuntz algebra QA. As an example of further applications of this technique we give a proof of the homotopy invariance of entire cyclic cohomology.

In this work, a Bayesian approach to speaker normalization is proposed to compensate for the degradation in performance of a speaker independent speech recognition system. The speaker normalization method proposed herein uses the technique of vocal tract length normalization (VTLN). The VTLN parameters are estimated using a novel Bayesian approach which utilizes the Gibbs sampler, a special typ...

Hyperlactatemia predicts mortality in patients with sepsis and septic shock, and its normalization is a potential treatment goal. We investigated the association of blood lactate and its changes over time with 90-day mortality in septic shock. We performed a post hoc analysis of 513 septic shock patients with admission blood lactate measurements in the prospective, observational, multicenter FI...

This paper presents new adaptive filtering techniques used in speech enhancement system. Adaptive filtering schemes are subjected to different trade-offs regarding their steady-state misadjustment, speed of convergence, and tracking performance. Fractional Least-Mean-Square (FLMS) is a new adaptive algorithm which has better performance than the conventional LMS algorithm. Normalization of LMS ...