After the seminal observation that reported initiation of AF by pulmonary vein arrhythmogenicity3 and subsequent contributions on pulmonary vein (PV) and non–PV-dependent mechanisms in the genesis of AF, percutaneous catheter ablation has rapidly evolved to eliminate both paroxysmal and persistent AF over the last decade. Numerous reports from registries and randomized clinical trials demonstra...

Surgical pulmonary vein isolation by ablation as a treatment for atrial fibrillation was first performed in isolation in 1996 at Hospital de Santa Cruz in Portugal, as a complementary therapy to mitral valve surgery in patients with rheumatic mitral valve disease, in order to reduce the morbidity associated with maze surgery. This innovative surgical approach, performed by Queiroz e Melo, repla...

introduction: the ablation technique is one of the important therapeutic interventions for treatment of av nodal tachyarrhythmia. different animal models have been developed to study the effects of ablation on the functional interanodal structure. the aim of the present study was to develop a new model of computer analysis to produce lesions by using direct voltage in isolated perfused rabbit a...

conclusions radiofrequency ablation may be used successfully in the treatment of parathyroid adenoma when a patient cannot tolerate surgery. case presentation a 47-year-old patient was referred to our hospital (namazi hospital, shiraz, iran) in april, 2015 with intracranial hemorrhage, as well as high serum calcium and pth (parathyroid hormone) levels (12.1 mg/dl and 1062 pg/ml, respectively), ...

This study reviews our experience in the surgical treatment of atrial fibrillation (AF) during the past 2 decades in 212 consecutive patients with lone AF. Freedom from AF in the original Cox-Maze III procedure was 93%. However, the procedure was difficult to perform and had a 10% rate of major complications. By using radiofrequency bipolar clamp technology to replace surgical incisions with tr...

av-node modification by catheter rf energy delivery is treatment of choice in the symptomatic patients with avnrt. this study included 30 patients with avnrt (19 women, 11 men). we did slow pathway ablation in 29 cases successfully. maximum effective energy delivery was 40 watts for 40 msec. 1:1 av conduction increased from 290±40 msec before ablation to 340±65 msec after ablation. also av-node...

Unilateral blockade of the dorsal hippocampus by tetrodotoxin makes it possible to form lateralized spatial memories, which rapidly transfer to the naive hippocampus when training continues with intact brain. Unilateral X-ray irradiation of newborn rats causes irreversible destruction of granule cells in the ipsilateral fascia dentata (FD). Possible compensation of poor learning in the lesioned...

In hypertrophic cardiomyopathy (HCM) atrial fibrillation (AF) has been historically described as unrelenting, a driver for heart failure, with decisive impact on quality of life. AF treatment deemed less effective in HCM due to high rates recurrence. However, predominantly characterized from physicians perspective and there is no data patient reported outcome measures (PROMs). To evaluate the P...