Journal:
:iranian red crescent medical journal
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fereshteh talebpour amiri department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, ir iran
fatemeh fadaei fathabadi department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, ir iran
mahnaz mahmoudi rad skin research centre, shahid beheshti university of medical sciences, tehran, ir iran; skin research centre, shahid beheshti university of medical sciences, tehran, ir iran. tel: +98-2122741512, fax: +98-2122027147
abbas piryae department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, ir iran
azar ghasemi department of pathology, faculty of medicine, mazandaran university of medical sciences, sari, ir iran
alireza khalilian department of biostatistics and social medicine, faculty of medicine, mazandaran university of medical sciences, sari, ir iran
conclusions this study indicated that the optimization of gene transfer increases the expression of igf-1. high concentrations of igf-1, in combination with cell therapy, have a significant effect on wound healing. results in vitro, the maximum expression of igf1 (96.95 pg/ml) in transfected fibroblast cells was 24 hours after gene transfer. in vivo, it was clear that igf-1 gene therapy caused ...