This summary is intended to update the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy (SBTMO) 2020/1 consensus on HSCT for Acute Myeloid leukemia (AML).

Gelatinous bone marrow transformation (GMT), also known as starvation marrow, represents a rare pathological entity of unclear etiology, in which bone marrow histopathology demonstrates hypoplasia, fat atrophy, and gelatinous infiltration. The finding of gelatinous marrow transformation lacks disease specificity; rather, it is an indicator of severe illness and a marker of poor nutritional stat...

Bone marrow fibrosis leading to dry tap aspiration and often associated with blast crisis has previously been reported in both Chronic myeloid leukemia Primary myelofibrosis.

background: there are multiple methods for acceleration of bone healing. bone marrow has been shown to contain osteoprogenitor cells.   objective: to determine the effect of percutaneous bone marrow injection on bone healing.   methods: 15 mature, 2-kg-weighing white new zealand rabbits from both sexes were randomized into 3 groups: group i: only osteotomy of right radius was performed and a 5 ...

Background: Pancytopenia is a Clinico-hematological entity, characterized by triad of Anemia, leucopenia, and thrombocytopenia. The criterion for defining HGB < 9 g/dl: ANC 1.5 x 109/L platelet count <100 109/L. main objective this study to categorize pediatric pancytopenia’s on etiological basis the age wise incidence.
 Methodology Results: This 5-year (2016-2021) conducted in terti...

Bone marrow cancer is considered to be the most complex and dangerous disease which results due an uncontrolled growth of white blood cells called leukocytes. Acute Lymphoblastic Leukemia (ALL) Multiple Myeloma (MM) are important categories bone cancers, induces a larger number in marrow, preventing production healthy cells. The advent Artificial Intelligence, especially machine deep learning, ...

primary myeloid sacrom (ms) is a rare tumor and even more rare in multiple organs with no evidence of bone marrow involvement. this report describes an unusual case of a 19-year-old male presenting scrotal ms with a history of subconjunctival ms, 5 months ago. bone marrow biopsies showed no evidence of acute leukemia. despite radiotherapy for first involvement and chemotherapy for second presen...

this study discusses the effect of complexes of chitosan grafted polyethylenimine(ch-pei) with plasmid dna on viability of mesenchymal stem cells(mscs) derived from human marrow. ch-pei/pdna nanoparticles were synthesized through the complex coacervation method using pires plasmid containing green fluorescent protein (gfp) gene. to confirm the complexation, samples were run through an agarose g...

Citral is a major constituent of Cymbopogon citratus or lemongrass oil. The anti-clastogenic effect of citral (20 mg/kg) was tested against the known mutagens cyclophoshamide, mitomycin-C and nickel metal (NiCl2) in mice. Micronucleus (MN) frequency was evaluated in both bone marrow and peripheral blood erythrocytes. The sampling was done after 24 h, 48 h and 72 h of clastogen treatment. Result...