Background Dural lesions in the anterior skull base may occur secondary to benign or malignant pathology that may be difficult to differentiate on imaging. Detailed clinical evaluation in many cases will narrow the differential diagnosis. In spite of using all the available information, in certain cases the underlying etiology of a lesion remains unclear. Participant We report a rare case of me...

Objective. Information about possible prognostic factors of the survival of patients with atypical and malignant meningiomas (AMM) is sparse. The aim of our study was to evaluate prognostic significance of apoptotic marker caspase-3 and apoptotic inhibitor survivin in a series of primary AMM. Methods. 86 AMM (76 atypical and 10 malignant) were analyzed. Caspase-3 and survivin expression was eva...

A malignant intracerebral nerve sheath tumour (MINST) is a variant of MPNST arising inside the brain. They are very rare tumours that aggressive and have strong metastatic potential. We report case recurrent lesion in brain 39 years male who presented as meningioma. It was finally reported MINST with histopathology immunohistochemistry. Surgical excision treatment choice. The patient on follow-...

It has always been a goal in the medical sciences to develop diagnostic and imaging strategies having a minimum or no invasiveness and/or obliterating need of further invasive investigations. The differentiation of benign versus malignant tumors on the basis of imaging findings has always been a diagnostic dilemma as there is always some degree of overlap of imaging characteristics in both the ...

Abstract BACKGROUND Cranial irradiation as part of prophylactic (PCI) or radical treatment for childhood malignancies can be associated with late consequences such radiotherapy induced meningioma. METHODS We are reporting 5 patients treated at our institute. RESULTS Case 1: 24y female received PCI Acute Lymphoblastic Leukemia the age 2, and developed right frontal meningioma which was resected ...

It is about a 33-year-old female, with a 36 weeks uncomplicated pregnancy and with signs of increased intracranial pressure. Hours after admission and an obstetric evaluation, uterine contraction started and the patient was taken to the delivery room, where she presented a partial motor seizure on the left side with secondary generalization and urine emission. A caesarean section was performed ...

PURPOSE Meningiomas are frequent intracranial or spinal neoplasms, which recur frequently and can show aggressive clinical behaviour. We elucidated the impact of the integrin inhibitor cilengitide on migration, proliferation, and radiosensitization of meningioma cells. EXPERIMENTAL DESIGN We analyzed integrin expression in tissue microarrays of human meningiomas and the antimeningioma propert...

OBJECTIVE We present a case of a meningioma in which photodynamic diagnosis (PDD) using 5-aminolevulinic acid was very useful in identifying the cranial involvement. CLINICAL PRESENTATION An 83-year-old woman presented with a bony, hard, immobile bulge in her left forehead. Computed tomographic scans showed a thickening in the left frontal bone with a flat mass underneath. Magnetic resonance ...

BACKGROUND Malignant intraventricular meningiomas are quite rare and may spread along the craniospinal axis or extraneurally. However, simultaneous cerebrospinal dissemination and distal extraneural metastasis has seldom been reported. CASE PRESENTATION A 51-year-old woman presented with recurrent anaplastic meningioma in the trigone of right lateral ventricle over a 1.5-year period. Suggeste...