Benign fibrous histiocytoma or dermatofibroma is one of the most common types of benign, cutaneous, soft tissue tumors, most often found in the middle-aged adults. The diagnosis of dermatofibroma/benign fibrous histiocytoma is usually straightforward if the typical morphological features are present. However, some diagnostic difficulties may arise when one is dealing with some unusual morpholog...

We present a case of recurrent extensive malignant fibrous histiocytoma of maxilla. The case is unusual because of its massive extent at presentation even after primary surgery and full course of radiotherapy and chemotherapy. Even such massive tumor can be excised successfully. Primary malignant histiocytoma is rare; and such huge tumor at presentation is also rare and favorable outcome even

Sarcomas are relatively resistant because of hypoxia. We previously demonstrated that the transcutaneous CO(2) therapy reduced hypoxic conditions in human malignant fibrous histiocytoma (MFH). Therefore, we hypothesized that transcutaneous CO(2) therapy could enhance the antitumor effect of radiation therapy in human MFH. Our purpose was to evaluate the effects of transcutaneous CO(2) therapy o...