background: plasmodium vivax is responsible for approximately 80 million malaria cases in the world. apical membrane antigen1 (ama-1) is a type i integral membrane protein present in all plasmo­dium species. ama-1 interferes in critical steps of invasion of human hepatocytes by sporo­zoites and red blood cells by merozoites and is one of the most immunodominant antigens for elicit­ing a protect...

The honor of the invitation to deliver the 24th Charles Franklin Craig Lecture is greatly enhanced for me by the presence of Dr. Lewis W. Hackett, my first chief, as our presiding officer. It is significant that the invitation to speak on Malaria Eradication comes so soon after the masterly 22nd Charles Franklin Craig Lerture on “Malaria Eradication-Growth of the Concept and its Application” by...

For a better understanding of the epidemiology of Plasmodium falciparum in an African savanna area, the authors have: (a) defined the real gametocyte reservoir in the native population; (b) followed the fluctuations of gametocytaemia throughout the transmission period; and (c) measured the infectiousness of malarious individuals to mosquitoes. The transversal surveys, in different villages of t...

BACKGROUND & OBJECTIVES The Meghalaya region had been considered free of malaria, but recently malaria cases in the foothills and valley areas raised concern that malaria transmission at high elevations may be increasing. This increase is associated with land use and land cover (LULC) changes. This LULC directly modifies larval habitats and affect the anopheline larval distribution patterns. ...

BACKGROUND In malarious areas, pregnant women are more likely to have detectable malaria than are their non-pregnant peers, and the excess risk of infection varies with gravidity. Pregnant women attending antenatal clinic for their first visit are a potential pragmatic sentinel group to track the intensity of malaria transmission; however, the relation between malaria prevalence in children, a ...