نتایج جستجو برای: major type

تعداد نتایج: 1868036  

Journal: :Diabetes 2008
Theresa A Aly Erin E Baschal Mohamed M Jahromi Maria S Fernando Sunanda R Babu Tasha E Fingerlin Adam Kretowski Henry A Erlich Pamela R Fain Marian J Rewers George S Eisenbarth

OBJECTIVE HLA-DRB1*03-DQB1*0201/DRB1*04-DQB1*0302 (DR3/4-DQ8) siblings who share both major histocompatibility complex (MHC) haplotypes identical-by-descent with their proband siblings have a higher risk for type 1A diabetes than DR3/4-DQ8 siblings who do not share both MHC haplotypes identical-by-descent. Our goal was to search for non-DR/DQ MHC genetic determinants that cause the additional r...

Journal: :European Heart Journal 2022

Abstract Background Type 2 diabetes mellitus (T2DM) is a known major risk factor for cardiovascular disease. Whilst the influence of traditional factors such as hypertension, hyperlipidaemia and smoking are well-established determinants adverse events (MACE) in subjects with T2DM, impact insulin resistance, non-dipping blood pressure heart rate status have not been adequately investigated. Purp...

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