BACKGROUND Magnesium is one of the most important minerals in the body. Although some studies reported that patients with cystic fibrosis (CF) lack magnesium, no international study has assessed the importance of oral magnesium supplementation in CF patients. OBJECTIVE We prospectively investigated the long-term effect of oral magnesium supplementation on respiratory muscle strength by using ...

Twenty patients, who underwent coronary revascularization without cardioplegic arrest, were given (during cardiopulmonary bypass) either magnesium chloride 16 mmol in 10 ml of water (magnesium group) or 10 ml of water alone (control group). Plasma and urinary magnesium concentrations were measured for 24 h after operation. ECG was recorded continuously during this period. QT intervals corrected...

Of the three magnesium fractions in plasma, free ionized magnesium (Mg2+) has the greatest biological activity. Accordingly, information concerning this form in plasma is of cardinal importance to investigations in biometry and human pathology. For this reason, we developed an indirect assay for ionized magnesium in which Mg2+ is determined as the difference between ultrafiltrable magnesium, as...

The following report is concerned with the study of magnesium metabolism in clinical and experimental hyperthyroidism. This first communication deals primarily with the ratio of diffusible magnesium to total serum magnesium in the hyperthyroid state. The general question of relationship of total serum magnesium to its ultrafiltrable fraction in 8 normal individuals has been discussed by Watchor...

Preliminary evidence has suggested that magnesium sulfate infusion reduces delayed ischemic neurological deficit and improves clinical outcome after aneurysmal subarachnoid hemorrhage. However, little is known about its site of action in vivo. We studied 22 aneurysmal subarachnoid hemorrhage patients with or without magnesium sulfate infusion for 10-14 days. Thirteen patients had external ventr...

Magnesium is an important intracellular element that is involved in numerous cellular functions. Deficiencies in magnesium may play an important role in the pathogenesis of migraine headaches by promoting cortical spreading depression, alteration of neurotransmitter release and the hyperaggregation of platelets. Given this multifaceted role of magnesium in migraine, the use of magnesium in both...

The essential mineral magnesium is involved in numerous physiological processes. Recommended dietary intake is often not met and a low magnesium status increases the risk for various diseases. Magnesium status is regulated by several magnesium transport systems either in cellular or paracellular pathways. Numerous drugs either interfere with magnesium absorption in the intestines or the reabsor...

Magnesium compounds have been used in the healthcare setting for many years. Over-the-counter (OTC) products like magnesium oxides and magnesium hydroxides (magaldrate, Antiflux, Lowsium, Riopan) are used as antacids; magnesium salicylates (Doan’s pills, Magan, Mobidin) are used as non-narcotic analgesics; and magnesium salts (Milk of Magnesia) are used for constipation. This article focuses on...

As a cofactor in numerous enzymatic reactions, magnesium fulfils various intracellular physiological functions. Thus, imbalance in magnesium status-primarily hypomagnesaemia as it is seen more often than hypermagnesaemia-might result in unwanted neuromuscular, cardiac or nervous disorders. Measuring total serum magnesium is a feasible and affordable way to monitor changes in magnesium status, a...