Four eyes of 2 patients with corneal edema due to Fuchs' endothelial dystrophy were treated with CXL using the standard protocol. Since no improvement in visual acuity, corneal clarity, thickness, or pain sensation was evident in any eye at month 12, 2 eyes of the 2 patients were retreated, this time, following intraoperative corneal dehydration with glycerol 70% drops. This retreatment also fa...

Keratosis follicularis spinulosa decalvans (KFSD) is a rare X linked disease which is characterised by follicular hyperkeratosis of the skin and corneal dystrophy. Seven male patients and six female carriers are described. Special attention has been paid to the dermatological and ophthalmic markers of KFSD in patients and carriers. The most prominent features present in the male patients were f...

Aim: To evaluate visual outcome and complications of penetrating keratoplasty. Materials and Methods: 30 cases underwent penetrating keratoplasty for optical and therapeutic purpose. Clinical examination and investigations were conducted. Indications, demographic profile, visual outcome and complications were assessed.Follow up period was 6 months. Results: 93.33% operated for optical and 6.67%...

BACKGROUND Unilateral lattice corneal dystrophy is a rare entity. OBJECTIVE To highlight the evidence of unilateral lattice corneal dystrophy in a young female. CASE A young 28 years old female presented to the outpatient department of Ophthalmology with slowly progressive diminution of vision in left eye for one month. On ophthalmological examination best corrected visual acuity (BCVA) was...

PURPOSE To characterize the phenotype of an autosomal dominant macular dystrophy and identify the chromosomal locus. METHODS Thirteen members of a four-generation, nonconsanguineous British family were examined clinically and also underwent automated perimetry, fundus fluorescein angiography, and fundus autofluorescence imaging. After informed consent was obtained, blood samples were taken fo...

Protein deglycase DJ-1 (Parkinson disease protein 7) is a 20 kDa protein encoded by PARK7 gene. It is also known as a redox-sensitive chaperone and sensor that protect cells against oxidative stress-induced cell death in many human diseases. Though increasing evidence implicates that DJ-1 may also participate in ocular diseases, the overview of DJ-1 in ocular diseases remains elusive. In this r...