AIM To evaluate the results of current reforms in Macedonian health sector. METHOD Description and situation analysis, covering the period 1991-1997, are focused on demographic and vital indicators, morbidity and mortality data, elements of health care system, legislation, health insurance, health care financing, and elements of health care reforms. RESULTS The Republic of Macedonia experie...

This study aimed to describe the epidemiology of repolarization dispersion (QT dispersion and Tpeak-Tend dispersion) and further describe their associated clinical correlates among uncontrolled arterial hypertension in type-2 Diabetics patient, in western region of the Republic of Macedonia. Abnormal ventricular repolarization is associated with increased cardiovascular risk. Data relating to t...

Genetic variation in the regulation, expression and activity of genes coding for Phase I, Phase II drug metabolizing enzymes (DMEs) and drug targets, can be defining factors for the variability in both the effectiveness and occurrence of drug therapy side effects. Information regarding the geographic structure and multi-ethnic distribution of clinically relevant genetic variations is becoming i...

The aim of this study was to evaluate the most common ABCB1 (MDR1, P-glycoprotein) polymorphisms in the population of R. Macedonia and compare the allele and haplotype frequencies with the global geographic data reported from different ethnic populations. The total of 107 healthy Macedonian individuals from the general population was included. Genotypes for the ABCB1 for three polymorphisms C12...

The genetic polymorphism affecting the CYP3A5 enzyme is responsible for inter-individual and interethnic variability in the metabolism of CYP3A5 substrates. The aim of this study was to analyze the distribution of the most common CYP3A5*3 allelic variants in the healthy population of R. Macedonia and to investigate if the allelic frequency falls within the assumed range for European Caucasians....

A positive association between acetaminophen intake and allergic diseases has recently been reported in developed countries with impaired oxidant/antioxidant balance and promotion of atopy as proposed underlying mechanisms. The aim of the study was to explore the relationship between acetaminophen intake and asthma, hay fever, and eczema in The Republic of Macedonia as a country with acetaminop...

PURPOSE Evaluation of age- and sex-specific differences of anthropometric parameters that were used as indicators of growth and nutritional status in children aged 6 and 7 years in R. Macedonia and their comparison with the WHO and NCHS reference values. MATERIAL AND METHODS The study included 580 children aged 6 to 7 years from different regions of R. Macedonia. Eighteen anthropometric param...

Kenk, Roman. The Planarians (Turbellaria: Tricladida Paludicola) of Lake Ohrid in Macedonia. Smithsonian Contributions to Zoology, number 280, 56 pages, 57 figures, 1978.—A revision is presented of the planarian fauna of the Lake Ohrid area, known for its richness in endemic species with limited distribution. Apart from the already known four endemic species of Phagocata and ten species of Dend...

Advances in wireless communication technologies, such as wearable and implantable biosensors, along with recent developments in the embedded computing area are enabling the design, development, and implementation of body area networks. This class of networks is paving the way for the deployment of innovative healthcare monitoring applications. In the past few years, much of the research in the ...

Biological invasions usually start with a small number of founder individuals. These founders are likely to represent a small fraction of the total genetic diversity found in the source population. Our study set out to trace genetically the geographical origin of the horse-chestnut leafminer, Cameraria ohridella, an invasive microlepidopteran whose area of origin is still unkown. Since its disc...