OBJECTIVE Gestational diabetes is a risk factor for large-for-gestational-age (LGA) newborns, but many LGA babies are born to mothers with normal glucose tolerance. We aimed to clarify the association of maternal glycemia across the whole distribution with birth weight and risk of LGA births in mothers with normal glucose tolerance. RESEARCH DESIGN AND METHODS We undertook a population-based ...

Background Affective distress (clinically significant depression, anxiety and stress) central sensitization (CS) are consistently associated with the reported sensitivity severity of pain, physical disability, poor treatment outcomes, inflammatory disease activity, potentially early mortality in rheumatoid arthritis (RA). Objectives We aimed to explore affective patients RA determine how they c...

Chemotherapy-induced peripheral neurotoxicity (CIPN) seriously impairs patients' quality of life cumulatively and dose-dependently. Because assessment of CIPN usually depends on patients' subjective evaluation of symptoms, objective and quantitative measures are needed. We evaluated a point-of-care nerve conduction device (POCD), previously validated for the assessment of diabetic peripheral ne...

most current references recommend divided doses of prednisolone for the initial treatment of idiopathic minimal change nephrotic syndrome in children, with relapse occuring in the majority of them, but there is little experience concerning single-dose prednisolone therapy, especially considering the relapse rate. in this prospective study on 36 consecutive children with primary nephrotic syndro...

OBJECTIVE Medical weight loss could change sweet taste threshold and preferences. The decrease in sweet taste preferences may, in turn, help in the maintenance of weight loss. This study examined the association between sweet taste preferences at baseline and weight change during a medical weight management programme and the impact of diet-induced weight loss on sweet taste preferences. METHO...

We conducted a phase 3 randomized trial comparing 2 different doses of daunorubicin as induction chemotherapy in young adults (60 years of age or younger) with acute myeloid leukemia (AML). Of 383 patients who were analyzed, 189 received standard-dose daunorubicin (SD-DN, 45 mg/m² per day times 3 days) and 194 received high-dose daunorubicin (HD-DN, 90 mg/m² per day times 3 days) in addition to...

There are errors in Table 6, the last paragraph of the Experiment 1 Cognitive Estimation Task (CET) section, and Tables S6 and S7. Please view the correct paragraph and tables here: The distribution of the error scores for version A of the CET adjusted for age, gender and education is as follows: M = 4.11, Mdn = 4.00, SD = 3.32, minimum = -2, maximum = 21, interquartile range = 4.00. The distri...

Traits similar to those shown in autism spectrum condition (ASC) are apparent in relatives of individuals with ASC, and in the general population without necessarily meeting diagnostic criteria for an ASC. We assess whether the Autism-Spectrum Quotient (AQ), a self-report measure, has hierarchical properties using Mokken scaling. Hierarchical scales allow the presence of a latent trait to be id...

Abstract This study determined the choroidal thickness of senior (SN, n = 24) and middle-aged (MA, 17) healthy, mixed-breed mesocephalic dogs, both males (M) females (F), using spectral domain optical coherence tomography (SD-OCT). The dogs were divided into two groups for examination: MA (4–7 years old; 6 M, 11 F) SN (8–13 12 F). Choroidal was investigated SD-OCT radial linear scans. software ...