A 10 year old boy presented to our hospital with nephrotic syndrome relapse and signs of steroid toxicity in the form of posterior capsular cataract, affection of linear growth and stage 2 hypertension, in addition to steroid induced adiposity and fungal infection of the scalp resulting in cicatricial alopecia. He was diagnosed as nephrotic syndrome 6 months back. He went into remission with st...

cGVHD: chronic graft-vs-host disease HSCT: hematopoietic stem cell transplant INTRODUCTION Pili torti is a term that originates from Latin (pili meaning hair, torti meaning twisted) used to describe the irregularly flattened and twisted appearance of hair shafts on microscopic hair mount evaluation. Clinically, affected patients have fragile, coarse, and sparse hair. The 1808 rotation along the...

Acanthosis nigricans – an ill-defined, velvety, hyperpigmented plaque involving the fold of the skin, including the axilla, neck and groin Atrichia – absence of hair Atrophoderma – atrophy of the skin Blepharitis – inflammation of the eyelids Cicatricial alopecia – scarring alopecia Copy number variations – DNA segments with 1 kb or more of gains or losses Corneodesmosin – a protein found in co...

Primary cicatricial alopecias (PCA) are a diverse group of inflammatory hair disorders of unknown aetiology, clinically characterised by the loss of hair shafts, visible follicular ostia, and variable degrees of scalp inflammation. The hair follicle is the primary target of the disease process and persistent inflammation leads to irreversible damage to the hair follicle’s stem cells. Ultimately...

Background: Central Centrifugal Cicatricial Alopecia (CCCA) is a scarring hair loss that predominately affects women of African descent. The etiology unknown, however proposed to involve genetic, inflammatory, and environmental factors. Treatment includes anti-inflammatory therapies, such as intralesional steroids, topical oral antibiotics. However, effective, safe medical therapy often challen...

Hair loss, regardless of cause, can have a significant impact on self-esteem, mental health, and quality life. Early detection treatment help to improve outcomes lessen the emotional burden patients. Lichen planopilaris (LPP), frontal fibrosing alopecia (FFA), central centrifugal cicatricial (CCCA) are forms scarring that primarily affect women. Haircare professionals often first note signs sym...

A 48-year-old man, who was at risk for HBV infection as he worked as a nurse in an emergency department, received HBV vaccine Recombivax (Merck-Sharp & Dohme, MSD). The ¢rst dose of vaccine (1 ml) was given to the patient in July 1995 and the second (1ml) 4 weeks later. At the end of September 1995 the patient noted an eruption of numerous, polygonal, red and itchy papules localized on the trun...