Background: Recent studies show cardiovascular disease (CVD) risk factors have the tendency to intermingle. Integration between some biological and homodynamic risk factors have made the new hypothesis for etiology of CVDs. The aim of this study was to determine the clustering pattern of metabolic variables and left ventricular (LV) mass among smoker and non-smoker individuals and the interrela...

Background Transcatheter aortic valve implantation (TAVI) has become a common procedure for high-risk patients with severe aortic stenosis. Aortic regurgitation (AR) is commonly seen after TAVI, but little is known about how it evolves over time. Similarly, the impact of TAVI on left ventricular (LV) function, LV volumes and mass is not well defined.Paravalvular aortic regurgitation (AR) is fre...

OBJECTIVE To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. MATERIALS AND METHODS This study retrospectively enrolled 172 subjects (107 men and 65 women; age, 58 ± 10.9 years; body...

Methods A cross-sectional, population-based study of 4,593 participants ages 45 to 85 years, free of clinical cardiovascular disease. Retinal vascular calibers and retinopathy were graded from retinal photographs according to standardized protocols. The LV mass and volume were measured from cardiac magnetic resonance imaging. Extent of LV concentric remodeling was determined by the ratio of LV ...

Objectives. We sought to determine the relations of left atrial (LA) size to blood pressure, obesity, race, age and left ventricular (LV) mass in hypertension. Background. Although obesity, race and age may influence LV mass, their effects on LA size have not been defined in hypertension. Methods. Left atrial size was measured in 690 men (58% African-Americans) with mild to moderate hypertensio...

BACKGROUND The metabolic syndrome has been associated with cardiovascular disease, but few studies have examined its relationship with subclinical measures such as echocardiographic left ventricular (LV) mass. This relationship is likely to be of particular importance in blacks, in whom both the metabolic syndrome and LV hypertrophy are common. METHODS AND RESULTS Echocardiography, performed ...

BACKGROUND In congenital aortic stenosis, chronic pressure load has detrimental effects on left ventricular (LV) systolic and diastolic function. Reduction in LV pressure load with balloon aortic valvuloplasty (BAVP) may improve diastolic function. METHODS AND RESULTS Echocardiographic and catheterization data for 25 consecutive patients undergoing BAVP for congenital aortic stenosis were ret...

We investigated the influence of genetic predisposition to hypertension by studying the relation between insulin sensitivity and left ventricular (LV) mass and function in untreated lean and obese hypertensives. We selected 50 lean hypertensives with normotensive parents (negative family history of hypertension [F-]), 64 lean hypertensives with 1 or both parents hypertensive (positive family hi...

AIM It was the aim of our study to determine whether myocardial fibrosis influences physiologic or non-physiologic left ventricular (LV) hypertrophy in severe aortic stenosis. METHODS Myocardial fibrosis was evaluated using specimens taken from the ventricular septum in 79 patients submitted to aortic valve replacement because of symptomatic aortic stenosis. Patients were considered to have p...

BACKGROUND/AIMS There are few data on the effects of low hemoglobin levels on the left ventricle (LV) in patients without heart disease. The objective of this study was to document changes in the echocardiographic variables of LV structure and function after the correction of anemia without significant cardiovascular disease. METHODS In total, 34 iron-deficiency anemia patients (35 ± 11 years...