نتایج جستجو برای: lupus nephriti s
تعداد نتایج: 751321 فیلتر نتایج به سال:
OBJECTIVE Several confirmed genetic susceptibility loci for lupus have been described. To date, no clear evidence for genetic epistasis in lupus has been established. The aim of this study was to test for gene-gene interactions in a number of known lupus susceptibility loci. METHODS Eighteen single-nucleotide polymorphisms tagging independent and confirmed lupus susceptibility loci were genot...
Nearly one half of patients with lupus develop glomerulonephritis (GN), which often leads to renal failure. Although nephritis is diagnosed by the presence of proteinuria, the pathology of nephritis can fall into one of five classes defined by different forms of tissue injury, and the mechanisms involved in pathogenesis are not completely understood. Glycosphingolipids are abundant in the kidne...
BACKGROUND AND OBJECTIVES Autoantibodies to complement C1q (anti-C1q) are associated with the diagnosis of lupus nephritis. In this study, we compare anti-C1q IgG with another complement autoantibody, anti-C3b IgG, as a biomarker of lupus nephritis and lupus nephritis flare. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Our investigation involved the Ohio SLE Study, a prospective observationa...
OBJECTIVE Despite highly expensive treatments, lupus nephritis remains a major cause of morbidity and mortality in patients with relapsing or refractory lupus nephritis. Meanwhile, experimental studies indicate that curcumin attenuates both the binding of autoantibodies from systemic lupus erythematosus patients to their cognate antigens and also the inflammatory responses of tumor necrosis fac...
Introduction: Raynaudchr(chr(chr('39')39chr('39'))39chr(chr('39')39chr('39')))s is a common phenomenon that is also seen in connective tissue diseases such as polymyositis, lupus and mixed connective tissue diseases. However, its occurrence is more pronounced in systemic sclerosis. This phenomenon can be so severe that it leads to cyanosis and gangrene of the fingertips in the final stages. In ...
Immune complexes (ICs) play a pivotal role in causing inflammation in systemic lupus erythematosus (SLE). Yet, it remains unclear what the dominant blood cell type(s) and inflammation-related gene programs stimulated by lupus ICs are. To address these questions , we exposed normal human PBMCs or CD14 + isolated monocytes to SLE ICs in the presence or absence of C1q and performed microarray anal...
- ahmadi, m., kaboli, m., imani harsini, j., khosravi sharifabadi, r., almasi, m., 2012. strategic management plan for wolf (canis lupus) in hamedan province: an approach to reducing human-wolf conflicts. journal of natural environment, iranian journal of natural resources. 65, 271–281. - ballard, w.b., dau, j.r., 1983. characteristics of gray wolf, canis lupus, den and rendezvous sites in ...
normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: to determine the prevalence of cryoglobulins in iranian patients with systemic lupus erythematosus (sle) and evaluate the correlation of cryoglobulins with disease activity in these patients. materials and methods: in a cross-sectional study, we investigated 80 consecutive women who fulfilled the 1982 revised c...
conclusions post immunization lv is a rare complication of the bcg vaccine and should be considered by any physician. lupus vulgaris is a paucibacillary form of tb. therefore, acid fast bacilli are not detected in most cases. the pcr is a useful method for confirmation of the diagnosis of lv. introduction lupus vulgaris (lv) is one type of cutaneous tuberculosis (tb) but a rare complication of ...
Proliferative lupus nephritis is a strong predictor of morbidity and mortality in patients with systemic lupus erythematosus. Despite improvements in the management of lupus nephritis, a significant number of the patients do not respond to immunosuppressive therapy and progress to end-stage renal failure. In order to optimise the diagnostic strategy and treatment of patients with proliferative ...
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