A cohort of survivors of congenital diaphragmatic hernia (CDH), with matched controls, was studied to assess growth, respiratory function, and exercise performance. Nineteen of 24 survivors from an 11 year period (79%) were compared with 19 matched controls. Subjects had detailed auxology, performed spirometry and cycle ergometry, and completed questionnaires about respiratory symptoms and exer...

Wheezing during infancy has been linked to early loss of pulmonary function. We prospectively investigated the relation between bronchial hyperresponsiveness (BHR) and progressive impairment of pulmonary function in a cohort of asthmatic infants followed until age 9 years. We studied 129 infants who had had at least three episodes of wheezing. Physical examinations, baseline lung function tests...

We prospectively assessed the frequency of pulmonary complications and the natural course of lung function after bone marrow transplantation (BMT), as well as the effect of several risk factors in a homogeneous group of 39 children who underwent allogeneic or autologous BMT for haematological malignancies between 1992 and 1995. Four patients developed pneumonia within the first 3 months and thr...

As a rational approach to the many lung function tests available, we have subjected the results of a battery of six lung function measurements made in 458 coalminers to the statistical technique of principal components analysis. By this means the six test results were reduced to three principal components without important loss of information. The first component appeared to represent lung size...

The effects of cannabis on lung function remain unclear and may be different from those of tobacco. We compared the associations between use of these substances and lung function in a population-based cohort (n = 1,037). Cannabis and tobacco use were reported at ages 18, 21, 26 and 32 yrs. Spirometry, plethysmography and carbon monoxide transfer factor were measured at 32 yrs. Associations betw...

introduction executive function define as ability to maintain a suitable and gool directed condition for problem solving. the results of previous studies on tourette syndrome (ts) were contradiction, but the impairment of visual-spatial performance, working memory and reaction time were shown. in children with attention defiat hyperactivity disorder (adhd) impairment of set shifting, motor inhi...

Objective: To evaluate spirometric patterns of respiratory disorders and their relationship with functional severity and maximal expiratory flows at low lung volumes in patients with cystic fibrosis (CF). Methods: A retrospective cross-sectional study including adolescents and adults with CF. All of the patients were submitted to spirometry. Patients were classified as having preserved respirat...

ostoperative pain and breathless-ness following lung cancer surgery are important causes of disability. The prospect of such symptoms may influence the decision to proceed with surgery. Incapacitating intercostal neu-ralgia, unlike other surgical pain, often does not go away. Intolerable breathless-ness caused by removing lung tissue from a patient who already has poor lung function can result ...

BACKGROUND Chronic obstructive lung disease frequently leads to disability. Older patients may experience transitions between states of disability and independence over time. OBJECTIVE To identify factors associated with transition between states of disability and independent function in obstructive lung disease. METHODS We analyzed data on 4,394 participants in the Cardiovascular Health St...