The paper presents a case study on the synthesis of labelled transition systems (LTSs) for process calculi, choosing as testbed Cardelli and Gordon’s Mobile Ambients (MAs). The proposal is based on a graphical encoding: each process is mapped into a graph equipped with suitable interfaces, such that the denotation is fully abstract with respect to the usual structural congruence. Graphs with in...

1. The isolated perfused rat liver efficiently takes up cysteinyl leukotrienes (LTs) C4, D4, E4 and N-acetylLTE4 from circulation. More than 70 of these cysteinyl LTs are excreted from liver into bile within I h of onset of a 5 min infusion, while about 5 remain in the liver. About 20 of infused N-acetyl-LTE4 escapes hepatic first-pass extraction under our conditions. 2. Metabolites of LTC4 app...

Stimulus-evoked inhibitory events have not been demonstrated in thalamic spike trains encoding of pain and temperature stimuli. We have now tested the hypothesis that the human thalamic response to mechanical and thermal stimuli is characterized by low-threshold calcium spike (LTS)-associated bursts of high-frequency action potentials preceded by prolonged inhibition. The results included 57 ne...

The cysteinyl leukotrienes (cys-LTs), leukotriene (LT) C(4), LTD(4), and LTE(4), are smooth muscle constrictors that signal via the CysLT(1) receptor. Here we report that the cys-LTs play an important role in chronic pulmonary inflammation with fibrosis induced by bleomycin in mice. Targeted disruption of LTC(4) synthase, the pivotal enzyme for cys-LT biosynthesis, protected significantly again...

We have previously shown that estrogen-dependent growth enhancement of murine transformed Leydig cells (B-1 F) is mediated through inhibition of arachidonic acid metabolite formation. In the present study, the growth-inhibitory ability of leukotrienes (LTs) on B-1 F cells in serum-free culture was directly addressed. All peptidyl LTs (LTC4, LTD4, and LTE4) inhibited B-1 F cell growth in a dose-...

In order to capture all permissible implementations, partial models of component based systems are given as at the system level. However, iterative refinement by engineers is often more convenient at the component level. In this paper, we address the problem of decomposing partial behaviour models from a single monolithic model to a component-wise model. Specifically, given a Modal Transition S...

Field trials of the LTS-3 system at Keesler Air Force Base have been extended, and excellent results have been obtained with high-aptitude students, who had been excluded from earlier trials. A study of the use of the LTS for task simulation has led to the implementation of a new student response interpretation feature for the system. Design of the microfiche selector/reader breadboard for LTS-...

6500 Background: Little is known about the use of routine preventive care and cancer surveillance in long-term colorectal cancer survivors. NSABP LTS-01 is a study that examines the use of such services in long-term colorectal cancer survivors previously treated in NSABP adjuvant trials. METHODS Long-term colorectal cancer survivors (≥ 5 years) were recruited from five completed NSABP treatme...

ôbjective: this study has been conducted to investigate the efficacy of short-term dynamic psychotherapy on love trauma syndrome (lts) in female students. lts includes a constellation of intensive signs and symptoms which appear following the breakdown of a romantic relationship after a long time. ït interrupts person's function in many areas (academic, social or professional) and leads to...

Background and purpose: Machine learning is a class of modern and strong tools that can solve many important problems that nowadays humans may be faced with. Support vector regression (SVR) is a way to build a regression model which is an incredible member of the machine learning family. SVR has been proven to be an effective tool in real-value function estimation. As a supervised-learning appr...